Super-resolution infrared microspectroscopy reveals heterogeneous distribution of photosensitive lipids in human hair medulla.
Calcium carboxylate
Hair medulla
Lipids
OPTIR
Photodamage
Synchrotron-µFTIR
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
01 Mar 2023
01 Mar 2023
Historique:
received:
25
10
2022
revised:
24
11
2022
accepted:
27
11
2022
pubmed:
10
12
2022
medline:
4
1
2023
entrez:
9
12
2022
Statut:
ppublish
Résumé
Human hair medulla chemical composition appears mostly homogenous when mapped by FTIR microspectroscopy even when using a synchrotron radiation source (SR-μFTIR) but it is expected to be heterogeneous. We performed sub-micron chemical mapping of hair cortex and medullas using Optical Photothermal Infrared microspectroscopy (OPTIR) and a mid-infrared Quantum Cascade Laser (QCL) source covering the fingerprint and the CH stretching region. Photodamages were observed in the hair cortex at mild laser power and occurred in the hair medulla even at the lowest power settings of the IR QCL pulsed at 100 kHz rate (4 μW/μm
Identifiants
pubmed: 36493565
pii: S0039-9140(22)00948-1
doi: 10.1016/j.talanta.2022.124152
pii:
doi:
Substances chimiques
Calcium
SY7Q814VUP
Lipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
124152Informations de copyright
Copyright © 2022 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.