The Role of Bone Morphogenetic Protein Receptor Type 2 (
bone morphogenetic protein receptor type 2
disease modeling
induced pluripotent stem cell
pulmonary arterial endothelial cells
pulmonary arterial hypertension
pulmonary arterial smooth muscle cells
pulmonary vascular resistance
vascular remodeling
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
29 Nov 2022
29 Nov 2022
Historique:
received:
09
11
2022
revised:
25
11
2022
accepted:
25
11
2022
entrez:
11
12
2022
pubmed:
12
12
2022
medline:
15
12
2022
Statut:
epublish
Résumé
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by increased pulmonary vascular resistance (PVR), causing right ventricular hypertrophy and ultimately death from right heart failure. Heterozygous mutations in the bone morphogenetic protein receptor type 2 (
Identifiants
pubmed: 36497082
pii: cells11233823
doi: 10.3390/cells11233823
pmc: PMC9741276
pii:
doi:
Substances chimiques
BMPR2 protein, human
EC 2.7.11.30
Bone Morphogenetic Protein Receptors, Type II
EC 2.7.11.30
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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