Identification of Risk Factors for Sexual Dysfunction after Multimodal Therapy of Locally Advanced Rectal Cancer and Their Impact on Quality of Life: A Single-Center Trial.
multimodal therapy
quality of life
rectal cancer
sexual dysfunction
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
24 Nov 2022
24 Nov 2022
Historique:
received:
24
10
2022
revised:
13
11
2022
accepted:
22
11
2022
entrez:
11
12
2022
pubmed:
12
12
2022
medline:
12
12
2022
Statut:
epublish
Résumé
Sexual function is crucial for the quality of life and can be highly affected by preoperative therapy and surgery. The aim of this study was to identify potential risk factors for poor sexual function and quality of life. Female patients were asked to complete the Female Sexual Function Index (FSFI-6). Male patients were demanded to answer the International Index of Erectile Function (IIEF-5). In total, 79 patients filled in the questionary, yielding a response rate of 41.57%. The proportion of women was represented by 32.91%, and the median age was 76.0 years (66.0-81.0). Sexual dysfunction appeared in 88.46% of female patients. Severe erectile dysfunction occurred in 52.83% of male patients. Univariate analysis showed female patients (OR: 0.17, 95%CI: 0.05-0.64, Higher Age, female sex, distal tumors and extensive surgery (APR, ISR) are revealed risk factors for SD in this study. Quality of life was only affected in the case of APR or ISR.
Identifiants
pubmed: 36497279
pii: cancers14235796
doi: 10.3390/cancers14235796
pmc: PMC9736520
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Langenbecks Arch Surg. 2022 Nov;407(7):2945-2957
pubmed: 35849193
Eur J Cancer. 2009 Jun;45(9):1578-88
pubmed: 19147343
Adv Psychosom Med. 2008;29:23-32
pubmed: 18391555
Updates Surg. 2021 Dec;73(6):2155-2159
pubmed: 34236596
Asian J Surg. 2018 Sep;41(5):454-461
pubmed: 28800864
Br J Surg. 1982 Oct;69(10):613-6
pubmed: 6751457
Int J Impot Res. 1999 Dec;11(6):319-26
pubmed: 10637462
Urology. 1997 Jun;49(6):822-30
pubmed: 9187685
J Gastrointest Surg. 2011 Aug;15(8):1375-85
pubmed: 21557014
Asian J Surg. 2022 Jan;45(1):39-50
pubmed: 34362620
Dis Colon Rectum. 2011 Jan;54(1):113-25
pubmed: 21160322
Br J Surg. 2020 Apr;107(5):525-536
pubmed: 31792944
Ann Surg. 2021 Dec 1;274(6):e1223-e1229
pubmed: 32097165
Ann Surg. 2005 Aug;242(2):212-23
pubmed: 16041212
Asian J Surg. 2016 Oct;39(4):225-31
pubmed: 26340884
Eur J Surg Oncol. 2021 Aug;47(8):2087-2092
pubmed: 33832775
Tech Coloproctol. 2014 Nov;18(11):993-1002
pubmed: 25056719
Dis Colon Rectum. 2009 Jan;52(1):46-54
pubmed: 19273955
BMC Cancer. 2021 Jun 10;21(1):682
pubmed: 34112100
Ann Coloproctol. 2014 Oct;30(5):210-5
pubmed: 25360427
Colorectal Dis. 2015 Jan;17(1):26-37
pubmed: 25156386
J Sex Med. 2010 Mar;7(3):1139-46
pubmed: 19968774
Front Oncol. 2022 Apr 22;12:853662
pubmed: 35530321
Ann Surg Oncol. 2005 Feb;12(2):117-23
pubmed: 15827791
Eur J Surg Oncol. 2018 Jul;44(7):1031-1039
pubmed: 29665980
Dis Colon Rectum. 2002 Sep;45(9):1178-85
pubmed: 12352233
ANZ J Surg. 2004 Apr;74(4):248-59
pubmed: 15043737
Int J Colorectal Dis. 2017 Nov;32(11):1523-1530
pubmed: 28497404
Nat Rev Urol. 2011 Jan;8(1):51-7
pubmed: 21135876
J Visc Surg. 2010 Feb;147(1):e21-30
pubmed: 20587375
World J Surg. 2005 Feb;29(2):190-7
pubmed: 15654662
Ann Surg. 2004 Aug;240(2):205-13
pubmed: 15273542
Ann Oncol. 2017 Jul 1;28(suppl_4):iv22-iv40
pubmed: 28881920
Anaesthesia. 1995 Jul;50(7):658-9
pubmed: 7653772