Clinical Characterization of the Three Waves of COVID-19 Occurring in Southern Italy: Results of a Multicenter Cohort Study.
COVID-19
SARS-CoV-2
clinical outcome
mortality
pandemic waves
Journal
International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455
Informations de publication
Date de publication:
30 Nov 2022
30 Nov 2022
Historique:
received:
05
10
2022
revised:
24
11
2022
accepted:
26
11
2022
entrez:
11
12
2022
pubmed:
12
12
2022
medline:
15
12
2022
Statut:
epublish
Résumé
To characterize patients hospitalized for COVID-19 in the three waves in Southern Italy. We conducted a multicenter observational cohort study involving seventeen COVID-19 Units in Campania, southern Italy: All adult (≥18 years) patients, hospitalized with a diagnosis of SARS-CoV-2 infection from 28 February 2020 to 31 May 2021, were enrolled. Two thousand and fifteen COVID-19 hospitalized patients were enrolled; 392 (19%) in the first wave, 917 (45%) in the second and 706 (35%) in the third wave. Patients showed a less severe clinical outcome in the first wave than in the second and third waves (73%, 65% and 72%, respectively; Improved organization of the healthcare facilities and the increase in knowledge of clinical and therapeutic management have contributed to a trend in the reduction in mortality during the three waves of COVID-19.
Identifiants
pubmed: 36498078
pii: ijerph192316003
doi: 10.3390/ijerph192316003
pmc: PMC9738780
pii:
doi:
Types de publication
Observational Study
Multicenter Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : POR Campania FESR 2014-2020-
ID : Avviso per l'acquisizione di manifestazioni di interesse per la realizzazione di servizi di ricerca e sviluppo per la lotta contro il Covid-19 (DGR n. 140 del 17 marzo 2020),
Organisme : POR FESR Campania 2014 - 2020
ID : Avviso per l'acquisizione di manifestazioni di interesse da parte degli Organismi di Ricerca per la realizzazione di servizi di ricerca, sviluppo e innovazione per la lotta contro il Covid-19 (DGR n. 504 del 10.11.2021)
Références
N Engl J Med. 2021 Feb 25;384(8):693-704
pubmed: 32678530
Trials. 2020 Jun 26;21(1):574
pubmed: 32586394
Int J Environ Res Public Health. 2022 Oct 28;19(21):
pubmed: 36360974
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Intern Emerg Med. 2022 Oct;17(7):1941-1949
pubmed: 35809152
JAMA. 2020 Jun 9;323(22):2338-2340
pubmed: 32412606
Glob Health Med. 2021 Apr 30;3(2):56-59
pubmed: 33937565
Front Oncol. 2021 May 07;11:662746
pubmed: 34026639
BMJ Open. 2021 Oct 25;11(10):e052777
pubmed: 34697120
Metabolism. 2021 Apr;117:154373
pubmed: 32949592
PLoS One. 2020 Aug 26;15(8):e0238215
pubmed: 32845926
Front Aging Neurosci. 2021 Jun 29;13:698184
pubmed: 34267649
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Intensive Care Med. 2020 Dec;46(12):2248-2251
pubmed: 33170330
BMJ Open. 2022 Jan 3;12(1):e054069
pubmed: 34980623
J Intern Med. 2021 Apr;289(4):450-462
pubmed: 33020988
Aging Clin Exp Res. 2021 Jan;33(1):193-199
pubmed: 33345291
JAMA. 2020 Apr 7;323(13):1239-1242
pubmed: 32091533
Blood Transfus. 2022 May;20(3):263-264
pubmed: 34694221
Pulmonology. 2022 May-Jun;28(3):181-192
pubmed: 33824084
Clin Microbiol Infect. 2020 Jul;26(7):948.e1-948.e3
pubmed: 32360780
Lancet. 2021 May 01;397(10285):1637-1645
pubmed: 33933206
N Engl J Med. 2020 Apr 30;382(18):1708-1720
pubmed: 32109013
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Pol Arch Intern Med. 2022 Oct 21;132(10):
pubmed: 35791725
Swiss Med Wkly. 2021 Jul 19;151:w20572
pubmed: 34324697
Eur Respir J. 2020 May 14;55(5):
pubmed: 32217650
Int J Environ Res Public Health. 2020 Jul 14;17(14):
pubmed: 32674450