Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner.
T cell apoptosis
antigen specificity
severe COVID-19
tolerance
tolerogenic dendritic cells
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
02 Dec 2022
02 Dec 2022
Historique:
received:
09
11
2022
revised:
28
11
2022
accepted:
29
11
2022
entrez:
11
12
2022
pubmed:
12
12
2022
medline:
15
12
2022
Statut:
epublish
Résumé
Although the global pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still ongoing, there are currently no specific and highly efficient drugs for COVID-19 available, particularly in severe cases. Recent findings demonstrate that severe COVID-19 disease that requires hospitalization is associated with the hyperactivation of CD4
Identifiants
pubmed: 36499533
pii: ijms232315201
doi: 10.3390/ijms232315201
pmc: PMC9740551
pii:
doi:
Substances chimiques
Antigens
0
Peptides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Research Foundation - Flanders
ID : G049320N
Organisme : Research Foundation - Flanders
ID : 1S37319N
Organisme : Research Foundation - Flanders
ID : 1861219N
Organisme : Fondation Charcot
ID : Charcot Fonds 2021
Organisme : UZA foundation
ID : This funding has no reference number
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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