Can Crude Oil Exploration Influence the Phytochemicals and Bioactivity of Medicinal Plants? A Case of Nigerian

Ocimum gratissimum leaves UPLC-QTOF-MS Vernonia amygdalina leaves drug design in silico metabolomics molecular docking pharmacophore sickle cell anaemia

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
30 Nov 2022
Historique:
received: 19 10 2022
revised: 26 11 2022
accepted: 27 11 2022
entrez: 11 12 2022
pubmed: 12 12 2022
medline: 15 12 2022
Statut: epublish

Résumé

The Nigerian Niger-Delta crude oil exploration often results in spills that affect indigenous medicinal plant biodiversity, likely changing the phytochemical profile of surviving species, their bioactivity or toxicity. In crude oil-rich Kokori and crude oil-free Abraka, classic examples of indigenous plants occupying the medicine-food interface include

Identifiants

pubmed: 36500460
pii: molecules27238372
doi: 10.3390/molecules27238372
pmc: PMC9740812
pii:
doi:

Substances chimiques

Petroleum 0
Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Schlumberger Faculty for the future grant
ID : XXXXXXXX

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Auteurs

Oluwatofunmilayo A Diyaolu (OA)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

Emmanuel T Oluwabusola (ET)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

Alfred F Attah (AF)

Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin 240003, Nigeria.

Eric O Olori (EO)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ibadan, Ibadan 200005, Nigeria.

Adeshola A Fagbemi (AA)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Lead City University, Ibadan 200255, Nigeria.

Gagan Preet (G)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

Sylvia Soldatou (S)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

Jones O Moody (JO)

Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Ibadan 200005, Nigeria.

Marcel Jaspars (M)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

Rainer Ebel (R)

Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.

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Classifications MeSH