Cholinesterases Inhibition, Anticancer and Antioxidant Activity of Novel Benzoxazole and Naphthoxazole Analogs.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
03 Dec 2022
Historique:
received: 31 10 2022
revised: 29 11 2022
accepted: 01 12 2022
entrez: 11 12 2022
pubmed: 12 12 2022
medline: 15 12 2022
Statut: epublish

Résumé

Benzoxazole and naphthoxazole fused systems are found in many biologically active molecules. Novel benzoxazole and naphthoxazole analogs functionalized by the 2,4-dihydroxyphenyl moiety were designed, obtained and evaluated as a broad spectrum of biological potency compounds. Sulfinylbis[(2,4-dihydroxyphenyl)methanethione] or its analogs and 2-aminophenols or 1-amino-2-naphthol were used as starting reagents. 4-(Naphtho[1,2-

Identifiants

pubmed: 36500605
pii: molecules27238511
doi: 10.3390/molecules27238511
pmc: PMC9738531
pii:
doi:

Substances chimiques

Benzoxazoles 0
Cholinesterase Inhibitors 0
Antioxidants 0
Oxazoles 0
Acetylcholinesterase EC 3.1.1.7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Bioorg Med Chem. 2007 May 1;15(9):3201-7
pubmed: 17350846
Biomolecules. 2019 Dec 12;9(12):
pubmed: 31842463
Bioorg Med Chem Lett. 2016 Jul 1;26(13):3067-3072
pubmed: 27209235
Bioorg Chem. 2017 Oct;74:82-90
pubmed: 28772160
J Antibiot (Tokyo). 2001 Jan;54(1):102-4
pubmed: 11269707
Bioorg Chem. 2022 Jul;124:105832
pubmed: 35500502
Mol Med Rep. 2019 Aug;20(2):1479-1487
pubmed: 31257471
Molecules. 2018 Sep 25;23(10):
pubmed: 30257495
Bioorg Chem. 2021 Feb;107:104617
pubmed: 33444983
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2609-13
pubmed: 20231096
Bioorg Med Chem Lett. 2004 Jun 21;14(12):3221-6
pubmed: 15149679
Molecules. 2021 Nov 26;26(23):
pubmed: 34885751
J Enzyme Inhib Med Chem. 2013 Aug;28(4):816-23
pubmed: 22630076
Molecules. 2020 Jun 03;25(11):
pubmed: 32503288
Chem Biol Drug Des. 2017 Nov;90(5):987-994
pubmed: 28544428
J Med Chem. 2006 Nov 30;49(24):6958-71
pubmed: 17125249
Eur J Med Chem. 2013 Apr;62:311-9
pubmed: 23376249
Molecules. 2012 Jan 17;17(1):873-83
pubmed: 22252503
Org Lett. 1999 Aug 12;1(3):527-30
pubmed: 10822593
Eur J Med Chem. 2000 Apr;35(4):393-404
pubmed: 10858600
Bioorg Chem. 2019 Feb;82:211-223
pubmed: 30326403
Eur J Med Chem. 2021 Jan 15;210:112979
pubmed: 33183865
Int J Mol Sci. 2022 Aug 25;23(17):
pubmed: 36077036
Bioorg Med Chem. 2006 Jul 1;14(13):4483-9
pubmed: 16517170
J Chem Inf Comput Sci. 1987 Feb;27(1):21-35
pubmed: 3558506
J Mol Graph Model. 2000 Aug-Oct;18(4-5):512-24, 541
pubmed: 11143566
Eur J Med Chem. 2018 Jan 1;143:970-982
pubmed: 29232587
Bioorg Med Chem. 2002 Dec;10(12):3997-4004
pubmed: 12413851
Chem Biol Drug Des. 2017 May;89(5):783-789
pubmed: 27863021
PLoS One. 2014 Sep 03;9(9):e106186
pubmed: 25184280
Molecules. 2022 Apr 11;27(8):
pubmed: 35458662
Molecules. 2021 Apr 20;26(8):
pubmed: 33924091
Bio Protoc. 2016 Nov 5;6(21):
pubmed: 28573164
JAMA Netw Open. 2019 Jun 5;2(6):e196167
pubmed: 31225887
Biochim Biophys Acta. 2014 Aug;1842(8):1240-7
pubmed: 24189435
Arch Pharm Res. 2011 Oct;34(10):1639-47
pubmed: 22076764
Eur J Med Chem. 2019 Feb 1;163:116-135
pubmed: 30503937
Arch Pharm (Weinheim). 2011 Apr;344(4):224-30
pubmed: 21469171
Bioorg Med Chem. 2006 Sep 1;14(17):6106-19
pubmed: 16714116
Food Chem. 2013 May 1;138(1):414-20
pubmed: 23265506
Eur J Med Chem. 2017 Sep 29;138:761-773
pubmed: 28728108
Z Naturforsch C J Biosci. 2016 Nov 1;71(11-12):409-413
pubmed: 27505087
J Org Chem. 2006 Mar 3;71(5):1802-8
pubmed: 16496964
J Med Chem. 1971 Jun;14(6):546-9
pubmed: 4326401
J Bacteriol. 1934 Apr;27(4):325-40
pubmed: 16559703
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jan 24;118:448-53
pubmed: 24080575
Pharmacol Res. 2004 Oct;50(4):433-40
pubmed: 15304240
Bioorg Med Chem. 2008 Feb 15;16(4):1775-83
pubmed: 18037301

Auteurs

Alicja Skrzypek (A)

Department of Chemistry, University of Life Sciences, Akademicka 15, 20-950 Lublin, Poland.

Monika Karpińska (M)

Institute of Industrial Organic Chemistry, Łukasiewicz Research Network, Annopol 6, 03-236 Warsaw, Poland.

Małgorzata Juszczak (M)

Department of Medical Biology, Institute of Rural Health, Jaczewskiego 2, 20-090 Lublin, Poland.

Aneta Grabarska (A)

Department of Biochemistry and Molecular Biology, Medical University, Chodźki 1, 20-090 Lublin, Poland.

Joanna Wietrzyk (J)

Department of Experimental Oncology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland.

Elżbieta Krajewska-Kułak (E)

Department of Integrated Medical Care, Medical University, M. Skłodowska-Curie 7A, 15-094 Białystok, Poland.

Marek Studziński (M)

Department of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry, Maria Curie-Skłodowska University, Pl. M. C. Skłodowkiej 3, 20-031 Lublin, Poland.

Tadeusz Paszko (T)

Department of Chemistry, University of Life Sciences, Akademicka 15, 20-950 Lublin, Poland.

Joanna Matysiak (J)

Department of Chemistry, University of Life Sciences, Akademicka 15, 20-950 Lublin, Poland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH