Safety profile and long-term efficacy of very high-power short-duration (60-70 W) catheter ablation for atrial fibrillation: results of a large comparative analysis.


Journal

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
ISSN: 1532-2092
Titre abrégé: Europace
Pays: England
ID NLM: 100883649

Informations de publication

Date de publication:
16 02 2023
Historique:
received: 25 06 2022
accepted: 30 09 2022
pubmed: 13 12 2022
medline: 22 2 2023
entrez: 12 12 2022
Statut: ppublish

Résumé

This retrospective study sought to compare complication rates and efficacy of power-controlled very high-power short-duration (vHPSD) and conventional catheter ablation in a large cohort of patients with atrial fibrillation (AF). We analyzed 1115 consecutive patients with AF (38.7% paroxysmal, 61.3% persistent) who received first-time catheter ablation at our centre from 2015 to 2021. Circumferential pulmonary vein isolation ± additional substrate ablation using an irrigated-tip catheter was performed with vHPSD (70 W/5-7 s or 60 W/7-10 s) in 574 patients and with conventional power (30-35 W/15-30 s) in 541 patients. Baseline characteristics were well-balanced between groups (mean age 65.1 ± 11.2 years, 63.4% male). The 30-day incidence of cardiac tamponade [2/574 (0.35%) vs. 1/541 (0.18%), P = 0.598], pericardial effusion ≥ 10 mm [2/574 (0.35%) vs. 1/541 (0.18%), P = 0.598] and transient ischaemic attack [1/574 (0.17%) vs. 2/541 (0.37%), P = 0.529] was not significantly different between vHPSD and conventional ablation. No stroke, atrio-esophageal fistula, cardiac arrest or death occurred. Procedure (122.2 ± 46.8 min vs. 155.0 ± 50.5 min, P < 0.001), radiofrequency (22.4 ± 19.3 min vs. 52.9 ± 22.0 min, P < 0.001), and fluoroscopy (8.1 ± 7.2 vs. 9.2 ± 7.4, P = 0.016) duration were significantly shorter in the vHPSD group. At 12 months follow-up, freedom of any atrial arrhythmia was 44.1% vs. 34.2% (P = 0.010) in persistent AF and 78.1% vs. 70.2% in paroxysmal AF (P = 0.068). vHPSD ablation is as safe as conventional ablation and is associated with an improved long-term efficacy in persistent AF.

Identifiants

pubmed: 36504120
pii: 6887868
doi: 10.1093/europace/euac215
pmc: PMC9935037
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

408-416

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

Déclaration de conflit d'intérêts

Conflict of interest: None declared.

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Auteurs

Miruna A Popa (MA)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Felix Bourier (F)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Sarah Lengauer (S)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Hannah Krafft (H)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Fabian Bahlke (F)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Leonie V Förschner (LV)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Stephan Dorfmeister (S)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Susanne Kathan (S)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Marta Telishevska (M)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Florian Englert (F)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Carsten Lennerz (C)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Tilko Reents (T)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Gabriele Hessling (G)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Isabel Deisenhofer (I)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

Marc Kottmaier (M)

German Heart Center Munich, Department of Electrophysiology, Lazarettstraße 36, 80636 Munich, Germany.
Munich Arrhythmia Research and Study Center (MARS), Lazarettstraße 36, 80636 Munich, Germany.

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