Gestational Intraplacental Choriocarcinoma in a Term Pregnancy: A Case Report.
choriocarcinoma
gestational trophoblastic disease
oncology
placenta
pregnancy
trophoblasts
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
accepted:
08
11
2022
entrez:
12
12
2022
pubmed:
13
12
2022
medline:
13
12
2022
Statut:
epublish
Résumé
Intraplacental choriocarcinoma (IC) is a rare type of gestational choriocarcinoma (GC) occurring within the placenta, and only a small number of cases have been reported so far. Intraplacental choriocarcinoma is usually asymptomatic or may present with aspecific symptoms, including unexplained vaginal bleeding during pregnancy. Early diagnosis and treatment are pivotal for ensuring optimal outcomes. However, intraplacental choriocarcinoma is rarely suspected due to limited knowledge and awareness of the condition. Here, we report the case of a 34-year-old woman diagnosed with intraplacental choriocarcinoma by placental histological examination performed after delivery due to unexplained vaginal bleeding at 29 gestational weeks, requiring hospital admission. Two lines of chemotherapy and surgery were necessary to achieve complete remission. Since unexplained vaginal bleeding during pregnancy can be a clinical manifestation of intraplacental choriocarcinoma, we propose to consider placental histological examination in all pregnancies with this complication.
Identifiants
pubmed: 36505145
doi: 10.7759/cureus.31243
pmc: PMC9731319
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e31243Informations de copyright
Copyright © 2022, Sala et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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