Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience.
children
oxygen enrichment therapy
post operative treatment
sinus pilonidalis
wound healing
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
12
10
2022
accepted:
14
11
2022
entrez:
12
12
2022
pubmed:
13
12
2022
medline:
13
12
2022
Statut:
epublish
Résumé
Pilonidal disease (PD) is a common infectious and inflammatory condition affecting the gluteal cleft and sacrococcygeal region. The optimal treatment for PD remains controversial. While the open technique reduces the number of relapses compared to minimally invasive approaches, it is associated with a longer healing time. Reactive oxygen species are a key part of the normal wound-healing process. Herein, we reported our preliminary experience using a new oxygen-enriched oil-based product called NovoX for wound healing after open surgery for PD. We used a new oxygen-enriched product for wound healing in three pediatric patients undergoing open surgical repair for PD between December 2021 and April 2022. During postoperative follow-up, healing time and the aesthetic result were evaluated. Our preliminary study included three patients with chronic PD. The average follow-up time was 5 weeks, corresponding to the end of the healing process and the resumption of normal daily activities. Only one mild complication occurred during the study period. No short-term side effects were reported. The cosmetic result was reported as satisfactory. NovoX is easy to apply, safe, and effective for treating pediatric patients undergoing open surgical treatment for PD, leading to slightly faster wound healing with good aesthetic outcomes.
Identifiants
pubmed: 36507121
doi: 10.3389/fped.2022.1068280
pmc: PMC9732366
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1068280Informations de copyright
© 2022 Bisol, Tykhomyrova, Pagliara, Scarpa, Guida, Olenik, Codrich, Schleef and Boscarelli.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
World J Surg. 2013 Sep;37(9):2074-80
pubmed: 23732258
Tech Coloproctol. 2016 Feb;20(2):139-40
pubmed: 26643941
Colorectal Dis. 2009 Sep;11(7):705-10
pubmed: 18637924
Acta Chir Belg. 2017 Jun;117(3):164-168
pubmed: 28056720
Br J Dermatol. 2010 Aug;163(2):257-68
pubmed: 20394633
Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006213
pubmed: 20091589
Saudi Med J. 2005 Apr;26(4):553-5
pubmed: 15900358
Aesthet Surg J Open Forum. 2021 May 04;3(3):ojab016
pubmed: 34131642
J Pediatr Surg. 2019 Nov;54(11):2210-2221
pubmed: 30948198
J Pediatr Surg. 2019 Nov;54(11):2222-2233
pubmed: 30940347
JAMA Surg. 2016 Jun 1;151(6):547-53
pubmed: 26819186
Curr Surg. 2004 May-Jun;61(3):307-12
pubmed: 15165772
Int Wound J. 2017 Feb;14(1):89-96
pubmed: 26688157
Adv Pediatr. 2022 Aug;69(1):231-241
pubmed: 35985713
Clinics (Sao Paulo). 2010 Feb;65(2):125-31
pubmed: 20186294
Langenbecks Arch Surg. 2016 Aug;401(5):599-609
pubmed: 27311698
Front Pediatr. 2020 Jun 24;8:345
pubmed: 32671004
Ann Burns Fire Disasters. 2021 Jun 30;34(2):170-174
pubmed: 34584506
J Pediatr Surg. 2009 Jan;44(1):282-5
pubmed: 19159757
Am Surg. 2013 Dec;79(12):1263-8
pubmed: 24351353
Adv Wound Care (New Rochelle). 2015 Jul 1;4(7):431-439
pubmed: 26155386
Curr Opin Pediatr. 2018 Jun;30(3):411-416
pubmed: 29553956
J Wound Care. 2014 Feb;23(2):53-4, 56-7
pubmed: 24526080
Acta Dermatovenerol Alp Pannonica Adriat. 2017 Mar;26(1):15-17
pubmed: 28352930