Oxygen-enriched oleic matrix (NovoX) for wound healing in pediatric patients undergoing open surgical treatment for pilonidal disease: Preliminary experience.

children oxygen enrichment therapy post operative treatment sinus pilonidalis wound healing

Journal

Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492

Informations de publication

Date de publication:
2022
Historique:
received: 12 10 2022
accepted: 14 11 2022
entrez: 12 12 2022
pubmed: 13 12 2022
medline: 13 12 2022
Statut: epublish

Résumé

Pilonidal disease (PD) is a common infectious and inflammatory condition affecting the gluteal cleft and sacrococcygeal region. The optimal treatment for PD remains controversial. While the open technique reduces the number of relapses compared to minimally invasive approaches, it is associated with a longer healing time. Reactive oxygen species are a key part of the normal wound-healing process. Herein, we reported our preliminary experience using a new oxygen-enriched oil-based product called NovoX for wound healing after open surgery for PD. We used a new oxygen-enriched product for wound healing in three pediatric patients undergoing open surgical repair for PD between December 2021 and April 2022. During postoperative follow-up, healing time and the aesthetic result were evaluated. Our preliminary study included three patients with chronic PD. The average follow-up time was 5 weeks, corresponding to the end of the healing process and the resumption of normal daily activities. Only one mild complication occurred during the study period. No short-term side effects were reported. The cosmetic result was reported as satisfactory. NovoX is easy to apply, safe, and effective for treating pediatric patients undergoing open surgical treatment for PD, leading to slightly faster wound healing with good aesthetic outcomes.

Identifiants

pubmed: 36507121
doi: 10.3389/fped.2022.1068280
pmc: PMC9732366
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1068280

Informations de copyright

© 2022 Bisol, Tykhomyrova, Pagliara, Scarpa, Guida, Olenik, Codrich, Schleef and Boscarelli.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Marta Bisol (M)

Division of Pediatric Surgery, Department of Women's and Children's Health, University of Padua, Padua, Italy.

Sophia Tykhomyrova (S)

Municipal Non-Profit Enterprise "Lviv Territorial Medical Union", Multidisciplinary Clinical Hospital of Emergency and Intensive Care - Separated Division "Hospital of Saint Nicolaus", Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.

Camilla Pagliara (C)

Division of Pediatric Surgery, Department of Women's and Children's Health, University of Padua, Padua, Italy.

Maria-Grazia Scarpa (MG)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Edoardo Guida (E)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Damiana Olenik (D)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Daniela Codrich (D)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Jürgen Schleef (J)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.
Chief of Surgical Department, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Alessandro Boscarelli (A)

Department of Pediatric Surgery and Urology, Institute of Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy.

Classifications MeSH