Characteristics of unvaccinated and vaccinated critically ill COVID-19 patients in calabria region (Italy): A retrospective study.
COVID-19
acute respiratory failure
booster vaccination
critical care
gas exchange
vaccination
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2022
2022
Historique:
received:
12
09
2022
accepted:
10
11
2022
entrez:
12
12
2022
pubmed:
13
12
2022
medline:
13
12
2022
Statut:
epublish
Résumé
After the rapid surge of a novel coronavirus (SARS-CoV-2) in 2020 anti-SARS-CoV-2 vaccines have been developed to prevent the development of critical forms of COVID-19 leading to Intensive Care Unit (ICU) admission. The possibility of ICU admission after the first-cycle vaccination has been already reported; however, no data have been published regarding vaccinated patients with a "booster" dose. This retrospective study describes the characteristics of critically ill patients after the implementation of the regional "booster" dose vaccination program in a southern region of Italy. We screened all medical records of critically ill COVID-19 patients in the period between January to April 2022. We collected the demographic characteristics, the presence of comorbidities, the vaccination status, the clinical course (arterial blood gases and type of respiratory support) and outcomes (rate of tracheostomy, ICU length of stay and mortality). A total of 272 patients were admitted to ICUs during the study period. 161 patients were unvaccinated, whereas 111 were vaccinated with the complete first-cycle or "booster" dose. The type of respiratory support was similar between groups. Vaccinated patients were characterized by a better oxygenation throughout the whole ICU length of stay. Fourteen unvaccinated and 3 vaccinated patients required tracheostomy ( Vaccinated patients have better clinical course and outcomes as compared to the unvaccinated population.
Identifiants
pubmed: 36507545
doi: 10.3389/fmed.2022.1042411
pmc: PMC9729689
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1042411Investigateurs
Antonio Caroleo
(A)
Paolo Chirico
(P)
Angela Corea
(A)
Silvia Corrado
(S)
Pierfrancesco De Luca
(P)
Federica Fazio
(F)
Martina Fontanella
(M)
Annamaria Froio
(A)
Cesira Greco
(C)
Giusy Guzzi
(G)
Marco Pignataro
(M)
Sara Rizzo
(S)
Claudia Roccia
(C)
Giuseppe Saraco
(G)
Ugo Settimio
(U)
Marco Tescione
(M)
Eugenio Vadalà
(E)
Michele Ippolito
(M)
Cosimo Stefano
(C)
Pietro Maglio
(P)
Mario Pezzi
(M)
Simona Tiburzi
(S)
Informations de copyright
Copyright © 2022 Bruni, Longhini, Macheda, Biamonte, Pasqua, Neri, Guzzo, Garofalo and Calabria COVID-ICU Network authors.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor declared a past co-authorship with one of the author FL.
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