Characteristics of γδTCR on myeloid cells from C57BL/6 mice with Plasmodium yoelii nigeriensis infection.

Animals Mice Flow Cytometry Malaria Mice, Inbred C57BL Myeloid Cells / metabolism Plasmodium yoelii / physiology Receptors, Antigen, T-Cell, gamma-delta
CD11b(+) γδTCR(+)cells Pathways Plasmodium yoelii nigeriensis

Journal

Molecular and biochemical parasitology
ISSN: 1872-9428
Titre abrégé: Mol Biochem Parasitol
Pays: Netherlands
ID NLM: 8006324

Informations de publication

Date de publication:
02 2023
Historique:
received: 08 08 2022
revised: 25 10 2022
accepted: 04 12 2022
pubmed: 13 12 2022
medline: 8 2 2023
entrez: 12 12 2022
Statut: ppublish

Résumé

Recently, there is a paucity of studies focus on the characteristics of myeloid cells which expressed γδTCR. The aim of this study was to observe the properties of γδTCR-expressing myeloid cells in the spleen of C57BL/6 mice infected by P. yoelii nigeriensis NSM. Haematoxylin-eosin (HE) staining was used to observe pathological changes in the spleens from infected mice. The differentially expressed genes (DEGs) between the infection and control groups were analyzed by RNA sequencing (RNA -seq). Flow cytometry (FCM) was used to evaluate the frequency of γδTCR

Identifiants

DOI: 10.1016/j.molbiopara.2022.111540 PMID: 36509228
pubmed: 36509228
pii: S0166-6851(22)00094-9
doi: 10.1016/j.molbiopara.2022.111540
pii:
doi:

Substances chimiques

Receptors, Antigen, T-Cell, gamma-delta 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

111540

Informations de copyright

Copyright © 2022. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Competing interests The authors declare that they have no competing interests.

Auteurs

Dianhui Chen (D)

Department of Infectious Diseases, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

Feng Mo (F)

Department of Infectious Diseases, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

Meiling Liu (M)

Clinical Laboratory, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

Yongjing Ma (Y)

Department of Gynaecology and Obstetrics, Heze Hospital of Traditional Chinese Medicine, Heze, Shandong 274000, China.

Lin Liu (L)

China Sino-French Hoffmann Institute, Department of basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.

Junmin Xing (J)

China Sino-French Hoffmann Institute, Department of basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.

Feihu Shi (F)

Department of Infectious Diseases, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.

Anqi Xie (A)

China Sino-French Hoffmann Institute, Department of basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.

Hongyan Xie (H)

China Sino-French Hoffmann Institute, Department of basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China.

Xingfei Pan (X)

Department of Infectious Diseases, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China. Electronic address: panxf0125@163.com.

Xinhua Wang (X)

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou, China; Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address: xinhuaw@gzhmu.edu.cn.

Jun Huang (J)

China Sino-French Hoffmann Institute, Department of basic Medical Science, Guangzhou Medical University, Guangzhou 511436, China. Electronic address: hj165@sina.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytophotométrie › Cytométrie en flux › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Infection › Maladies vectorielles › Paludisme › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Eucaryotes › Alveolata › Apicomplexa › Haemosporida › Plasmodium › Plasmodium yoelii › Characteristics of γδTCR on myeloid cells from...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › Récepteur lymphocytaire T antigène, gamma-delta › Characteristics of γδTCR on myeloid cells from...