Long-term air pollution exposure and Parkinson's disease mortality in a large pooled European cohort: An ELAPSE study.
Adults
Air pollution
Long-term exposure
Low-level exposure
Parkinson’s Disease
Pooled-cohort study
Journal
Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
received:
29
08
2022
revised:
22
11
2022
accepted:
27
11
2022
pubmed:
15
12
2022
medline:
24
1
2023
entrez:
14
12
2022
Statut:
ppublish
Résumé
The link between exposure to ambient air pollution and mortality from cardiorespiratory diseases is well established, while evidence on neurodegenerative disorders including Parkinson's Disease (PD) remains limited. We examined the association between long-term exposure to ambient air pollution and PD mortality in seven European cohorts. Within the project 'Effects of Low-Level Air Pollution: A Study in Europe' (ELAPSE), we pooled data from seven cohorts among six European countries. Annual mean residential concentrations of fine particulate matter (PM Of 271,720 cohort participants, 381 died from PD during 19.7 years of follow-up. In single-pollutant analyses, we observed positive associations between PD mortality and PM Long-term exposure to PM
Sections du résumé
BACKGROUND
The link between exposure to ambient air pollution and mortality from cardiorespiratory diseases is well established, while evidence on neurodegenerative disorders including Parkinson's Disease (PD) remains limited.
OBJECTIVE
We examined the association between long-term exposure to ambient air pollution and PD mortality in seven European cohorts.
METHODS
Within the project 'Effects of Low-Level Air Pollution: A Study in Europe' (ELAPSE), we pooled data from seven cohorts among six European countries. Annual mean residential concentrations of fine particulate matter (PM
RESULTS
Of 271,720 cohort participants, 381 died from PD during 19.7 years of follow-up. In single-pollutant analyses, we observed positive associations between PD mortality and PM
CONCLUSION
Long-term exposure to PM
Identifiants
pubmed: 36516478
pii: S0160-4120(22)00594-3
doi: 10.1016/j.envint.2022.107667
pii:
doi:
Substances chimiques
Air Pollutants
0
Nitrogen Dioxide
S7G510RUBH
Particulate Matter
0
Environmental Pollutants
0
Soot
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
107667Subventions
Organisme : Medical Research Council
ID : MR/S019669/1
Pays : United Kingdom
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.