Low thoracic skeletal muscle index is associated with negative outcomes in 244 patients with respiratory COVID-19.
COVID-19
Computed tomography
Emergency care
Sarcopenia
Skeletal muscle index
Journal
Clinical nutrition (Edinburgh, Scotland)
ISSN: 1532-1983
Titre abrégé: Clin Nutr
Pays: England
ID NLM: 8309603
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
13
06
2022
revised:
27
10
2022
accepted:
09
11
2022
pubmed:
16
12
2022
medline:
3
2
2023
entrez:
15
12
2022
Statut:
ppublish
Résumé
Sarcopenia is associated with negative outcomes in intensive care unit (ICU) patients and during chronic diseases. We aimed to evaluate if low skeletal muscle index (SMI) measured by computed tomography (CT) at the thoracic level is associated with poor outcomes in hospitalized patients with respiratory COVID-19. Patients admitted to the hospital between March 1st and June 9, 2020 with a confirmed diagnosis of respiratory COVID-19 in the Emergency Department were included in this retrospective cohort study. SMI was assessed from a transverse CT image at the T12 level. We analysed the association between thoracic SMI and mortality, ICU admissions, infections, length of stay and gravity scores. We included 244 patients, whose median age was 62 (20-95) years, mean body mass index was 28,6 kg/m Low SMI measured by CT at the thoracic level T12 is associated with negative outcomes in patients with respiratory COVID-19.
Sections du résumé
BACKGROUND
Sarcopenia is associated with negative outcomes in intensive care unit (ICU) patients and during chronic diseases. We aimed to evaluate if low skeletal muscle index (SMI) measured by computed tomography (CT) at the thoracic level is associated with poor outcomes in hospitalized patients with respiratory COVID-19.
METHODS
Patients admitted to the hospital between March 1st and June 9, 2020 with a confirmed diagnosis of respiratory COVID-19 in the Emergency Department were included in this retrospective cohort study. SMI was assessed from a transverse CT image at the T12 level. We analysed the association between thoracic SMI and mortality, ICU admissions, infections, length of stay and gravity scores.
RESULTS
We included 244 patients, whose median age was 62 (20-95) years, mean body mass index was 28,6 kg/m
CONCLUSION
Low SMI measured by CT at the thoracic level T12 is associated with negative outcomes in patients with respiratory COVID-19.
Identifiants
pubmed: 36521254
pii: S0261-5614(22)00396-X
doi: 10.1016/j.clnu.2022.11.011
pmc: PMC9674398
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102-107Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest None to declare.