The atrial secondary tricuspid regurgitation is associated to more favorable outcome than the ventricular phenotype.

We sought to evaluate the differences in prognosis between the atrial (A-STR) and the ventricular (V-STR) phenotypes of secondary tricuspid regurgitation. Consecutive patients with moderate or severe STR referred for echocardiography were enrolled. A-STR and V-STR were defined according to the last ACC/AHA guidelines criteria. The primary endpoint was the composite of all-cause death and heart failure (HF) hospitalizations. A total of 211 patients were enrolled. The prevalence of A-STR in our cohort was 26%. Patients with A- STR were significantly older and with lower NYHA functional class than V-STR patients. The prevalence of severe STR was similar (28% in A-STR vs. 37% in V-STR, Almost one-third of patients referred to the echocardiography laboratory for significant STR have A-STR. A-STR patients had a lower incidence of the combined endpoint than V-STR patients. Moreover, while TR severity was the only independent factor associated to outcome in A-STR patients, TR severity and RV function were independently associated with outcome in V-STR patients.

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Copyright © 2022 Gavazzoni, Heilbron, Badano, Radu, Cascella, Tomaselli, Perelli, Caravita, Baratto, Parati and Muraru.

Déclaration de conflit d'intérêts

Author MG receives personal fees from Abbot Vascular. Authors DM and LB were members of the speaker bureau of GE Healthcare and Philips Medical Systems, and received research support from GE Healthcare, Philips Medical Systems, and EsaOte. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The reviewer DM and handling editor declared their shared affiliation.