The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons.


Journal

Stem cells international
ISSN: 1687-966X
Titre abrégé: Stem Cells Int
Pays: United States
ID NLM: 101535822

Informations de publication

Date de publication:
2022
Historique:
received: 19 06 2022
revised: 10 11 2022
accepted: 11 11 2022
entrez: 19 12 2022
pubmed: 20 12 2022
medline: 20 12 2022
Statut: epublish

Résumé

Motor neurons (MNs) derived from human-induced pluripotent stem cells (hiPSC) hold great potential for the treatment of various motor neurodegenerative diseases as transplantations with a low-risk of rejection are made possible. There are many hiPSC differentiation protocols that pursue to imitate the multistep process of motor neurogenesis

Identifiants

pubmed: 36530489
doi: 10.1155/2022/1320950
pmc: PMC9757946
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1320950

Informations de copyright

Copyright © 2022 Catherine Schaefers et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

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Auteurs

Catherine Schaefers (C)

Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937 Munich, Germany.

Simone Rothmiller (S)

Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937 Munich, Germany.

Horst Thiermann (H)

Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937 Munich, Germany.

Theo Rein (T)

Max Planck Institute of Psychiatry, Kraepelinstr. 2-10, 80804 Munich, Germany.

Annette Schmidt (A)

Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937 Munich, Germany.
Institute of Sport Science, University of the Bundeswehr Munich, Werner-Heisenberg-Weg 39, 85577 Neubiberg, Germany.

Classifications MeSH