Safety of 2'-fucosyllactose (2'-FL) produced by a derivative strain (APC199) of
2’‐FL
2′‐fucosyllactose
HMO
HiMO
human milk oligosaccharide
novel food
safety
Journal
EFSA journal. European Food Safety Authority
ISSN: 1831-4732
Titre abrégé: EFSA J
Pays: United States
ID NLM: 101642076
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
entrez:
19
12
2022
pubmed:
20
12
2022
medline:
20
12
2022
Statut:
epublish
Résumé
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 2'-fucosyllactose (2'-FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human-identical milk oligosaccharide (HiMO) 2'-FL, but it also contains d-lactose, l-fucose, 3-fucosyllactose, difucosyllactose, d-glucose and d-galactose. The NF is produced by fermentation with a genetically modified strain (APC199) of
Identifiants
pubmed: 36531695
doi: 10.2903/j.efsa.2022.7647
pii: EFS27647
pmc: PMC9749449
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e07647Informations de copyright
© 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority.
Références
J Nutr. 2015 Aug;145(8):1698-708
pubmed: 26041675
EFSA J. 2022 May 04;20(5):e07257
pubmed: 35515337
Glycobiology. 2013 Jun;23(6):664-76
pubmed: 23436288
Am J Clin Nutr. 2017 May;105(5):1086-1100
pubmed: 28356278
Nutrients. 2016 Jun 08;8(6):
pubmed: 27338459
Glycobiology. 2006 Jun;16(6):477-87
pubmed: 16495330
Glycobiology. 2012 Sep;22(9):1147-62
pubmed: 22513036
Br J Nutr. 2010 Nov;104(9):1261-71
pubmed: 20522272
Eur J Clin Nutr. 2008 Apr;62(4):488-94
pubmed: 17375110
J Pediatr. 2004 Sep;145(3):297-303
pubmed: 15343178
EFSA J. 2022 May 16;20(5):e07242
pubmed: 35600267
J Pediatr Gastroenterol Nutr. 2006 Sep;43(3):372-8
pubmed: 16954962
Electrophoresis. 2014 Mar;35(6):811-8
pubmed: 24338619
Nutr Rev. 2017 Nov 01;75(11):920-933
pubmed: 29053807
Am J Clin Nutr. 2000 Jun;71(6):1589-96
pubmed: 10837303
Anal Biochem. 2012 Nov 1;430(1):97-104
pubmed: 22885238
EFSA J. 2019 Jun 11;17(6):e05717
pubmed: 32626339
J Pediatr Gastroenterol Nutr. 2017 May;64(5):789-798
pubmed: 27602704
EFSA J. 2022 Jan 27;20(1):e07045
pubmed: 35126735
EFSA J. 2021 Mar 26;19(3):e06555
pubmed: 33791039
Acta Paediatr. 1996 May;85(5):598-603
pubmed: 8827106
Acta Paediatr Suppl. 1999 Aug;88(430):89-94
pubmed: 10569230
Br J Nutr. 2017 Jan;117(2):237-247
pubmed: 28179042
Biosci Biotechnol Biochem. 2013;77(3):455-66
pubmed: 23470761
PLoS One. 2014 Jul 07;9(7):e101692
pubmed: 24999728
J Biol Chem. 2011 Oct 7;286(40):34583-92
pubmed: 21832085
Adv Exp Med Biol. 2001;501:285-97
pubmed: 11787692
EFSA J. 2021 Jun 30;19(6):e06662
pubmed: 34221147
EFSA J. 2017 Jul 25;15(7):e04918
pubmed: 32625578
Adv Exp Med Biol. 2001;501:307-14
pubmed: 11787695
Adv Exp Med Biol. 2001;501:315-23
pubmed: 11787697
J Nutr. 2013 Nov;143(11):1709-18
pubmed: 24027187
EFSA J. 2021 Jul 28;19(7):e06506
pubmed: 34335919
Regul Toxicol Pharmacol. 2015 Jun;72(1):39-48
pubmed: 25728407
EFSA J. 2018 Mar 28;16(3):e05206
pubmed: 32625840
EFSA J. 2020 Nov 19;18(11):e06305
pubmed: 33240437
EFSA J. 2022 May 25;20(5):e07329
pubmed: 35646167
J Nutr. 2000 Dec;130(12):3014-20
pubmed: 11110861
Nutrients. 2021 Aug 09;13(8):
pubmed: 34444897
Sci Rep. 2019 Aug 13;9(1):11767
pubmed: 31409852
EFSA J. 2019 Dec 03;17(12):e05907
pubmed: 32626198
Adv Nutr. 2012 May 01;3(3):398S-405S
pubmed: 22585918
EFSA J. 2022 Mar 03;20(3):e07140
pubmed: 35281646
J Pediatr. 1998 Jul;133(1):95-8
pubmed: 9672518
EFSA J. 2022 May 25;20(5):e07331
pubmed: 35646166
J Biol Chem. 2001 Sep 14;276(37):34363-70
pubmed: 11423546
J Pediatr Gastroenterol Nutr. 2000 Feb;30(2):181-92
pubmed: 10697138