MRI-quantified left atrial epicardial adipose tissue predicts atrial fibrillation recurrence following catheter ablation.

Dixon sequence atrial fibrillation cardiac magnetic resonance catheter ablation epicardial adipose tissue

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2022
Historique:
received: 16 09 2022
accepted: 21 11 2022
entrez: 19 12 2022
pubmed: 20 12 2022
medline: 20 12 2022
Statut: epublish

Résumé

Epicardial adipose tissue (EAT) plays a significant role in promoting atrial fibrillation (AF) due to its proinflammatory properties and anatomic proximity to the myocardium. We sought to assess whether left atrial (LA) EAT volume is associated with AF recurrence following catheter ablation. EAT was assessed During an average follow-up period of 1 year, post-ablation AF recurrence occurred in 31 (30.7%) patients. LA EAT index was higher in those with compared to without recurrence (20.7 [16.9, 30.4] vs. 13.7 [10.5, 20.1] mL/m EAT quantified using cardiac MRI, a reproducible and widely accessible imaging parameter, is a strong and independent predictor of post-ablation AF recurrence.

Sections du résumé

Background UNASSIGNED
Epicardial adipose tissue (EAT) plays a significant role in promoting atrial fibrillation (AF) due to its proinflammatory properties and anatomic proximity to the myocardium. We sought to assess whether left atrial (LA) EAT volume is associated with AF recurrence following catheter ablation.
Methods UNASSIGNED
EAT was assessed
Results UNASSIGNED
During an average follow-up period of 1 year, post-ablation AF recurrence occurred in 31 (30.7%) patients. LA EAT index was higher in those with compared to without recurrence (20.7 [16.9, 30.4] vs. 13.7 [10.5, 20.1] mL/m
Conclusion UNASSIGNED
EAT quantified using cardiac MRI, a reproducible and widely accessible imaging parameter, is a strong and independent predictor of post-ablation AF recurrence.

Identifiants

pubmed: 36531696
doi: 10.3389/fcvm.2022.1045742
pmc: PMC9755198
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1045742

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL158667
Pays : United States

Informations de copyright

Copyright © 2022 Chahine, Macheret, Ordovas, Kim, Boyle and Akoum.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Yaacoub Chahine (Y)

Division of Cardiology, University of Washington, Seattle, WA, United States.

Fima Macheret (F)

Division of Cardiology, University of Washington, Seattle, WA, United States.

Karen Ordovas (K)

Department of Radiology, University of Washington, Seattle, WA, United States.

Joonseok Kim (J)

Division of Cardiology, University of Washington, Seattle, WA, United States.

Patrick M Boyle (PM)

Department of Bioengineering, University of Washington, Seattle, WA, United States.
Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, United States.
Center for Cardiovascular Biology, University of Washington, Seattle, WA, United States.

Nazem Akoum (N)

Division of Cardiology, University of Washington, Seattle, WA, United States.
Department of Bioengineering, University of Washington, Seattle, WA, United States.

Classifications MeSH