Drug Repurposing: a Shortcut to New Biological Entities.
COVID-19
advantages
approaches
biological
computational
drug discovery
drug repurposing
methodologies
repurposed drugs
strategies
Journal
Pharmaceutical chemistry journal
ISSN: 0091-150X
Titre abrégé: Pharm Chem J
Pays: United States
ID NLM: 0323156
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
04
2021
entrez:
19
12
2022
pubmed:
20
12
2022
medline:
20
12
2022
Statut:
ppublish
Résumé
Drug repurposing has proved to be an efficient alternative to drug discovery owing to the facts that it is economical and risk factors being much lower or even negligible as the drug has already been approved for having safe use in humans. The contrast of drug discovery from drug repurposing, its advantages and the challenges faced during the process are the important factors to be considered in drug repurposing. The approaches in drug discovery include three methods namely computational, biological and mixed. Moreover, the recent advancement in application of drugs for COVID-19 proved drug repurposing is a vital strategy in medical science for the upcoming years.
Identifiants
pubmed: 36531825
doi: 10.1007/s11094-022-02778-w
pii: 2778
pmc: PMC9734433
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1203-1214Informations de copyright
© Springer Science+Business Media, LLC, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
Références
Nat Rev Drug Discov. 2004 Aug;3(8):673-83
pubmed: 15286734
Trends Cancer. 2017 Aug;3(8):543-546
pubmed: 28780930
J Clin Med. 2020 Jul 02;9(7):
pubmed: 32630746
Brief Bioinform. 2021 Mar 22;22(2):726-741
pubmed: 33147623
Indian J Pediatr. 2020 Apr;87(4):281-286
pubmed: 32166607
Biomed Pharmacother. 2019 Feb;110:700-716
pubmed: 30553197
Int J Surg. 2020 Apr;76:71-76
pubmed: 32112977
Brief Bioinform. 2018 Sep 28;19(5):878-892
pubmed: 28334136
J Pharm Pharmacol. 2020 Sep;72(9):1145-1151
pubmed: 32301512
Genome Med. 2012 Mar 30;4(3):27
pubmed: 22494857
Expert Opin Drug Discov. 2020 Apr;15(4):397-401
pubmed: 31847616
Pharmacol Rep. 2020 Dec;72(6):1479-1508
pubmed: 32889701
Biochem Pharmacol. 2020 Oct;180:114169
pubmed: 32710969
Int J Biol Sci. 2018 Jul 13;14(10):1232-1244
pubmed: 30123072
Cell. 2020 May 14;181(4):894-904.e9
pubmed: 32275855
Nat Rev Drug Discov. 2019 Jan;18(1):41-58
pubmed: 30310233
PLoS Comput Biol. 2009 Jul;5(7):e1000450
pubmed: 19649302