Ethionamide and Prothionamide Based Coumarinyl-Thiazole Derivatives: Synthesis, Antitubercular Activity, Toxicity Investigations and Molecular Docking Studies.
antitubercular activity
coumarin
cytotoxicity
molecular docking
synthesis
thiazole
Journal
Pharmaceutical chemistry journal
ISSN: 0091-150X
Titre abrégé: Pharm Chem J
Pays: United States
ID NLM: 0323156
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
06
2021
entrez:
19
12
2022
pubmed:
20
12
2022
medline:
20
12
2022
Statut:
ppublish
Résumé
The goal of this research work was to prepare and evaluate the antitubercular (anti-TB) activity of ethionamide (ETH) and prothionamide (PTH) based coumarinyl-thiazole derivatives. ETH and PTH were reacted with coumarin intermediates (
Identifiants
pubmed: 36531826
doi: 10.1007/s11094-022-02782-0
pii: 2782
pmc: PMC9734486
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1215-1225Informations de copyright
© Springer Science+Business Media, LLC, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
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