A short update on new approaches to celiac disease.
Journal
Acta bio-medica : Atenei Parmensis
ISSN: 2531-6745
Titre abrégé: Acta Biomed
Pays: Italy
ID NLM: 101295064
Informations de publication
Date de publication:
16 12 2022
16 12 2022
Historique:
received:
08
09
2022
accepted:
29
09
2022
entrez:
19
12
2022
pubmed:
20
12
2022
medline:
21
12
2022
Statut:
epublish
Résumé
Celiac disease is an autoimmune enteropathy of the small intestine, related to gluten intolerance occurring in genetically predisposed patients. Currently, the only available treatment is a lifelong gluten-free diet. However, the total avoidance of gluten is difficult and poses a challenge to patients, nutritionists and treating physicians. For this reason, scientists have developed in recent years new therapeutic approaches complementary to dietary treatment, such as modification of gluten to make gliadin non-toxic, reduction of the inflammatory response with elafin and Lactococcus Lactis, degradation of gluten by endoproteolytic enzymes, and correction of nutritional deficiencies by adding pseudo-cereals to the diet of celiac patients. This literature review focuses on the different treatment strategies for celiac disease previously studied and summarizes the latest advances in this field.
Identifiants
pubmed: 36533746
doi: 10.23750/abm.v93i6.13673
pmc: PMC9828896
doi:
Substances chimiques
Glutens
8002-80-0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2022322Références
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