Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.


Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
10 02 2023
Historique:
pubmed: 21 12 2022
medline: 14 2 2023
entrez: 20 12 2022
Statut: ppublish

Résumé

Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that follows benign COVID-19. We report autosomal recessive deficiencies of

Identifiants

pubmed: 36538032
doi: 10.1126/science.abo3627
pmc: PMC10451000
mid: NIHMS1915147
doi:

Substances chimiques

Cytokines 0
Endoribonucleases EC 3.1.-
RNA, Double-Stranded 0
OAS1 protein, human EC 2.7.7.-
OAS2 protein, human EC 2.7.7.-
2-5A-dependent ribonuclease EC 3.1.26.-
MAVS protein, human 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabo3627

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI127372
Pays : United States
Organisme : NHGRI NIH HHS
ID : UM1 HG006504
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI091707
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI104887
Pays : United States
Organisme : NIH HHS
ID : S10 OD018521
Pays : United States
Organisme : Intramural NIH HHS
ID : ZIA AI001270
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI088364
Pays : United States
Organisme : Medical Research Council
ID : MR/S032304/1
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : R01 AI130345
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI111825
Pays : United States
Organisme : NHGRI NIH HHS
ID : U24 HG008956
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001866
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI161444
Pays : United States
Organisme : NCI NIH HHS
ID : F99 CA274708
Pays : United States
Organisme : NIAID NIH HHS
ID : P01 AI138938
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI160576
Pays : United States

Investigateurs

Loubna Alavoine (L)
Sylvie Behillil (S)
Charles Burdet (C)
Charlotte Charpentier (C)
Aline Dechanet (A)
Diane Descamps (D)
Xavier Duval (X)
Jean-Luc Ecobichon (JL)
Vincent Enouf (V)
Wahiba Frezouls (W)
Nadhira Houhou (N)
Ouifiya Kafif (O)
Jonathan Lehacaut (J)
Sophie Letrou (S)
Bruno Lina (B)
Jean-Christophe Lucet (JC)
Pauline Manchon (P)
Mariama Nouroudine (M)
Valentine Piquard (V)
Caroline Quintin (C)
Michael Thy (M)
Sarah Tubiana (S)
Sylvie van der Werf (S)
Valérie Vignali (V)
Benoit Visseaux (B)
Yazdan Yazdanpanah (Y)
Abir Chahine (A)
Nawal Waucquier (N)
Maria-Claire Migaud (MC)
Dominique Deplanque (D)
Félix Djossou (F)
Mayka Mergeay-Fabre (M)
Aude Lucarelli (A)
Magalie Demar (M)
Léa Bruneau (L)
Patrick Gérardin (P)
Adrien Maillot (A)
Christine Payet (C)
Bruno Laviolle (B)
Fabrice Laine (F)
Christophe Paris (C)
Mireille Desille-Dugast (M)
Julie Fouchard (J)
Denis Malvy (D)
Duc Nguyen (D)
Thierry Pistone (T)
Pauline Perreau (P)
Valérie Gissot (V)
Carole Le Goas (C)
Samatha Montagne (S)
Lucie Richard (L)
Catherine Chirouze (C)
Kévin Bouiller (K)
Maxime Desmarets (M)
Alexandre Meunier (A)
Benjamin Lefèvre (B)
Hélène Jeulin (H)
Karine Legrand (K)
Sandra Lomazzi (S)
Bernard Tardy (B)
Amandine Gagneux-Brunon (A)
Frédérique Bertholon (F)
Elisabeth Botelho-Nevers (E)
Kouakam Christelle (K)
Leturque Nicolas (L)
Layidé Roufai (L)
Karine Amat (K)
Sandrine Couffin-Cadiergues (S)
Hélène Espérou (H)
Samia Hendou (S)
Laurent Abel (L)
Hassan Abolhassani (H)
Sergio Aguilera-Albesa (S)
Alessandro Aiuti (A)
Ozge Metin Akcan (OM)
Nihal Akcay (N)
Gulsum Alkan (G)
Suzan A Alkhater (SA)
Luis Miguel Allende (LM)
Yosunkaya Alper (Y)
Naima Amenzoui (N)
Mark S Anderson (MS)
Lisa Arkin (L)
Melodie Aubart (M)
Iryna Avramenko (I)
Şehnaz Aydemir (Ş)
Zeynep Gökçe Gayretli Aydin (ZG)
Caner Aytekin (C)
Gökhan Aytekin (G)
Selma Erol Aytekin (S)
Silvia Yumi Bando (SY)
Kathie Beland (K)
Serkan Belkaya (S)
Catherine M Biggs (CM)
Agurtzane Bilbao Aburto (A)
Geraldine Blanchard-Rohner (G)
Daniel Blázquez-Gamero (D)
Marketa Bloomfield (M)
Dusan Bogunovic (D)
Anastasia Bondarenko (A)
Alessandro Borghesi (A)
Amed Aziz Bousfiha (AA)
Oksana Boyarchuk (O)
Petter Brodin (P)
Yenan Bryceson (Y)
Giorgia Bucciol (G)
Valeria Calcaterra (V)
Giorgio Casari (G)
Andre Cavalcanti (A)
Jale Bengi Celik (JB)
George P Chrousos (GP)
Roger Colobran (R)
Antonio Condino-Neto (A)
Francesca Conti (F)
Megan Cooper (M)
Taner Coskuner (T)
Cyril Cyrus (C)
Enza D'Auria (E)
Selket Delafontaine (S)
Beth A Drolet (BA)
Burcu Bursal Duramaz (B)
Loubna El Zein (L)
Marwa H Elnagdy (MH)
Melike Emiroglu (M)
Emine Hafize Erdeniz (EH)
Marianna Fabi (M)
Hagit Baris Feldman (H)
Jacques Fellay (J)
Filip Fencl (F)
Filippos Filippatos (F)
Julie Freiss (J)
Jiri Fremuth (J)
Alenka Gagro (A)
Blanca Garcia-Solis (B)
Gianluca Vergine (G)
Rafaela González-Montelongo (R)
Yahya Gul (Y)
Belgin Gülhan (B)
Sara Sebnem Kilic Gultekin (SSK)
Marta Gut (M)
Rabih Halwani (R)
Lennart Hammarström (L)
Nevin Hatipoğlu (N)
James Heath (J)
Sarah E Henrickson (SE)
Elisa Hernandez-Brito (E)
Ilse Hoffman (I)
Levi Hoste (L)
Elena Hsieh (E)
Antonio Íñigo-Campos (A)
Yuval Itan (Y)
Petr Jabandziev (P)
Bahar Kandemir (B)
Saliha Kanık-Yüksek (S)
Hasan Kapakli (H)
Adem Karbuz (A)
Ozgur Kasapcopur (O)
Robin Kechiche (R)
Yasemin Kendir Demirkol (Y)
Omer Kilic (O)
Stella Kim Hansen (SK)
Adam Klocperk (A)
Yu-Lung Lau (YL)
Jan Lebl (J)
José M Lorenzo-Salazar (JM)
Carrie L Lucas (CL)
Majistor Maglorius (M)
Laura Marque (L)
Yeray Novoa Medina (Y)
Abián Montesdeoca Melián (A)
Alexios-Fotios A Mentis (AA)
Michele T Pato (MT)
Athanasios Michos (A)
Joshua D Milner (JD)
Trine H Mogensen (TH)
Adrián Muñoz-Barrera (A)
Serdar Nepesov (S)
João Farela Neves (J)
Ashley Ng (A)
Lisa F P Ng (LFP)
Antonio Novelli (A)
Giuseppe Novelli (G)
Fatma Nur Oz (FN)
J Gonzalo Ocejo-Viñals (JG)
Satoshi Okada (S)
Zerrin Orbak (Z)
Ahmet Osman Kilic (AO)
Hind Ouair (H)
Şadiye Kübra Tüter Öz (ŞKT)
Tayfun Özçelik (T)
Esra Akyüz Özkan (EA)
Aslınur Özkaya Parlakay (AÖ)
Carlos N Pato (CN)
Estela Paz-Artal (E)
Simon Pelham (S)
Isabelle Pellier (I)
Quentin Philippot (Q)
Laura Planas-Serra (L)
Samira Plassart (S)
Petra Pokorna (P)
Meltem Polat (M)
Cecilia Poli (C)
Carolina Prando (C)
Laurent Renia (L)
Jacques G Rivière (JG)
Agustí Rodríguez-Palmero (A)
Lucie Roussel (L)
Luis A Rubio-Rodriguez (LA)
Moro Salifu (M)
Lumir Sasek (L)
Laura Sasia (L)
Anna Scherbina (A)
Erica Schmitt (E)
Anna Sediva (A)
Esra Sevketoglu (E)
Katerina Slaba (K)
Ondrej Slaby (O)
Ali Sobh (A)
Jordi Solé-Violán (J)
Pere Soler-Palacin (P)
Lien De Somer (L)
Betül Sözeri (B)
András N Spaan (AN)
Yuriy Stepanovskiy (Y)
Stuart G Tangye (SG)
Gonul Tanir (G)
Elizabeth Barbara Tatsi (EB)
Christian W Thorball (CW)
Selda Hancerli Torun (S)
Stuart Turvey (S)
Mohammed J Uddin (MJ)
Emel Uyar (E)
Juan Valencia-Ramos (J)
Ana Maria Van Den Rym (AM)
Hulya Vatansev (H)
Martín Castillo de Vera (M)
François Vermeulen (F)
Donald C Vinh (DC)
Alla Volokha (A)
Horst von Bernuth (H)
Carine Wouters (C)
Aysun Yahşi (A)
Volkan Yarar (V)
Osman Yesilbas (O)
Mehmet Yıldız (M)
Mayana Zatz (M)
Pawel Zawadzki (P)
Gianvincenzo Zuccotti (G)
Shen-Ying Zhang (SY)
Jean-Laurent Casanova (JL)

Références

mBio. 2014 Feb 25;5(2):e00856-14
pubmed: 24570368
J Biol Chem. 1995 Feb 24;270(8):4133-7
pubmed: 7876164
J Infect Dis. 2021 Mar 3;223(5):785-795
pubmed: 33277988
Cell. 1993 Mar 12;72(5):753-65
pubmed: 7680958
BMB Rep. 2019 Feb;52(2):133-138
pubmed: 30078389
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3261-5
pubmed: 114998
J Interferon Cytokine Res. 2011 Jan;31(1):49-57
pubmed: 21190483
JAMA. 2020 Jul 21;324(3):259-269
pubmed: 32511692
J Clin Invest. 2020 Nov 2;130(11):5967-5975
pubmed: 32730233
Curr Protoc Microbiol. 2020 Jun;57(1):ecpmc105
pubmed: 32475066
J Clin Immunol. 2021 Apr;41(3):526-535
pubmed: 33394320
Elife. 2022 Jun 06;11:
pubmed: 35666101
J Exp Med. 2022 Aug 1;219(8):
pubmed: 35708626
Science. 2015 Jan 23;347(6220):1260419
pubmed: 25613900
Proc Natl Acad Sci U S A. 1978 Jan;75(1):256-60
pubmed: 272640
Nature. 2022 Jul;607(7917):97-103
pubmed: 35255492
Lancet Reg Health Eur. 2021 Jul;6:100109
pubmed: 33997835
Mol Cell. 2019 Sep 19;75(6):1203-1217.e5
pubmed: 31494035
Curr Opin Virol. 2015 Dec;15:19-26
pubmed: 26231767
J Immunol. 2009 Dec 15;183(12):8035-43
pubmed: 19923450
J Exp Med. 2021 Mar 1;218(3):
pubmed: 33231615
J Virol. 2013 Aug;87(15):8408-18
pubmed: 23698313
Nat Med. 2021 Apr;27(4):659-667
pubmed: 33633408
Science. 2020 Oct 23;370(6515):
pubmed: 32972995
Brain. 2021 Dec 31;144(12):3727-3741
pubmed: 34619763
Nature. 2021 Feb;590(7844):140-145
pubmed: 33137809
Am J Hum Genet. 2018 Mar 1;102(3):480-486
pubmed: 29455859
Cell Host Microbe. 2015 Apr 8;17(4):466-77
pubmed: 25816776
Nucleic Acids Res. 1981 Apr 10;9(7):1571-81
pubmed: 6164990
J Virol. 1983 Jun;46(3):1051-5
pubmed: 6190010
J Clin Invest. 2021 Jan 4;131(1):
pubmed: 32960813
PLoS Pathog. 2022 Apr 14;18(4):e1010464
pubmed: 35421191
Sci Immunol. 2021 Aug 19;6(62):
pubmed: 34413140
Nat Med. 2022 May;28(5):1050-1062
pubmed: 35177862
Nature. 1977 Aug 11;268(5620):537-40
pubmed: 560630
Int Immunopharmacol. 2014 Nov;23(1):37-45
pubmed: 25130606
Sci Immunol. 2021 Jun 18;6(60):
pubmed: 34145065
Cell. 2020 Nov 12;183(4):968-981.e7
pubmed: 32966765
Sci Immunol. 2021 May 25;6(59):
pubmed: 34035116
Arthritis Rheumatol. 2022 Apr;74(4):e1-e20
pubmed: 35118829
Nature. 2020 Nov;587(7835):610-612
pubmed: 32998156
Nature. 1980 Nov 13;288(5787):189-92
pubmed: 6159552
Nat Commun. 2021 Feb 17;12(1):1088
pubmed: 33597522
Nature. 2021 Mar;591(7848):92-98
pubmed: 33307546
MMWR Morb Mortal Wkly Rep. 2020 Oct 09;69(40):1450-1456
pubmed: 33031361
Rheumatology (Oxford). 2021 Oct 2;60(10):4530-4537
pubmed: 33493353
J Clin Invest. 2021 May 17;131(10):
pubmed: 33705359
J Virol. 1985 Jan;53(1):221-7
pubmed: 2981340
Science. 2020 Oct 23;370(6515):
pubmed: 32972996
FEBS Lett. 2013 Jan 16;587(2):156-64
pubmed: 23196181
Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2241-6
pubmed: 26858407
Cell Syst. 2015 Dec 23;1(6):417-425
pubmed: 26771021
Nature. 2020 Aug;584(7821):430-436
pubmed: 32640463
Cancer Res. 2003 Oct 15;63(20):6795-801
pubmed: 14583476
Nat Genet. 2022 Feb;54(2):125-127
pubmed: 35027740
Science. 2021 Nov 26;374(6571):1080-1086
pubmed: 34822298
J Virol. 2019 Jul 30;93(16):
pubmed: 31142667
Methods Mol Med. 2005;116:103-13
pubmed: 16000857
Med. 2021 Sep 10;2(9):1072-1092.e7
pubmed: 34414385
Sci Immunol. 2021 Mar 2;6(57):
pubmed: 33653907
J Virol. 2007 Dec;81(23):12720-9
pubmed: 17804500
Nat Rev Immunol. 2020 Aug;20(8):455-456
pubmed: 32555547
Immunity. 2021 May 11;54(5):1083-1095.e7
pubmed: 33891889
Nature. 2021 Dec;600(7889):472-477
pubmed: 34237774
JAMA Netw Open. 2021 Jun 1;4(6):e2116420
pubmed: 34110391
Eur J Epidemiol. 2020 Dec;35(12):1123-1138
pubmed: 33289900
JAMA. 2021 Mar 16;325(11):1074-1087
pubmed: 33625505
N Engl J Med. 2020 Jul 23;383(4):347-358
pubmed: 32598830
Nat Med. 2020 Nov;26(11):1701-1707
pubmed: 32812012
Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):
pubmed: 33408250
Eur J Pediatr. 2021 Jul;180(7):2019-2034
pubmed: 33599835
mBio. 2021 Aug 31;12(4):e0178121
pubmed: 34372695
Cell. 2020 Nov 12;183(4):982-995.e14
pubmed: 32991843
Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):
pubmed: 33593941
J Clin Invest. 2020 Nov 2;130(11):5942-5950
pubmed: 32701511
Science. 2021 Oct 29;374(6567):eabj3624
pubmed: 34581622
EClinicalMedicine. 2020 Sep;26:100527
pubmed: 32923992
RNA. 2001 Mar;7(3):361-73
pubmed: 11333017
Wiley Interdiscip Rev RNA. 2019 Jul;10(4):e1534
pubmed: 30989826
J Clin Invest. 2021 Mar 15;131(6):
pubmed: 33497356
Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14533-8
pubmed: 16203993
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):
pubmed: 33811184
Nat Immunol. 2006 Feb;7(2):131-7
pubmed: 16424890
Sci Immunol. 2021 Aug 19;6(62):
pubmed: 34413139
Cytometry A. 2023 Feb;103(2):136-145
pubmed: 33280254
Curr Pediatr Rep. 2021;9(4):83-92
pubmed: 34692237
J Exp Med. 2022 Feb 7;219(2):
pubmed: 34914824
J Exp Med. 2021 Jun 7;218(6):
pubmed: 33904890
Curr Rheumatol Rep. 2021 Jul 3;23(8):58
pubmed: 34216296
Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13615-20
pubmed: 26483451

Auteurs

Danyel Lee (D)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Jérémie Le Pen (J)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.

Ahmad Yatim (A)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Beihua Dong (B)

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Yann Aquino (Y)

Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.
Doctoral College, Sorbonne University, Paris, France.

Masato Ogishi (M)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Rémi Pescarmona (R)

Laboratory of Immunology, Lyon Sud Hospital, Lyon, France.

Estelle Talouarn (E)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Darawan Rinchai (D)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Peng Zhang (P)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Magali Perret (M)

Laboratory of Immunology, Lyon Sud Hospital, Lyon, France.

Zhiyong Liu (Z)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Iolanda Jordan (I)

Pediatric Intensive Care Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Kids Corona Platform, Barcelona, Spain.
Center for Biomedical Network Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
Respiratory and Immunological Dysfunction in Pediatric Critically Ill Patients, Institute of Recerca Sant Joan de Déu, Barcelona, Spain.

Sefika Elmas Bozdemir (S)

Bursa City Hospital, Bursa, Turkey.

Gulsum Iclal Bayhan (GI)

Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey.

Camille Beaufils (C)

Immunology and Rheumatology Division, Department of Pediatrics, University of Montreal, CHU Sainte-Justine, Montreal, QC, Canada.

Lucy Bizien (L)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Aurelie Bisiaux (A)

Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.

Weite Lei (W)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Milena Hasan (M)

Center for Translational Research, Institut Pasteur, Paris City University, Paris, France.

Jie Chen (J)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Christina Gaughan (C)

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Abhishek Asthana (A)

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Valentina Libri (V)

Center for Translational Research, Institut Pasteur, Paris City University, Paris, France.

Joseph M Luna (JM)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Department of Biochemistry and Center for RNA Science and Therapeutics, Case Western Reserve University, Cleveland, OH, USA.

Fabrice Jaffré (F)

Department of Surgery, Weill Cornell Medical College, New York, NY, USA.

H-Heinrich Hoffmann (HH)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.

Eleftherios Michailidis (E)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Department of Pediatrics, School of Medicine, Emory University, Atlanta, GA, USA.

Marion Moreews (M)

International Center of Infectiology Research (CIRI), University of Lyon, INSERM U1111, Claude Bernard University, Lyon 1, CNRS, UMR5308, ENS of Lyon, Lyon, France.

Yoann Seeleuthner (Y)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Kaya Bilguvar (K)

Departments of Neurosurgery and Genetics and Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT, USA.
Department of Medical Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.

Shrikant Mane (S)

Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.

Carlos Flores (C)

Research Unit, Nuestra Señora de la Candelaria University Hospital, Santa Cruz de Tenerife, Spain.
Genomics Division, Institute of Technology and Renewable Energies (ITER), Granadilla de Abona, Spain.
CIBERES, ISCIII, Madrid, Spain.

Yu Zhang (Y)

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.

Andrés A Arias (AA)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Primary Immunodeficiencies Group, University of Antioquia (UdeA), Medellin, Colombia.
School of Microbiology, University of Antioquia (UdeA), Medellin, Colombia.

Rasheed Bailey (R)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Agatha Schlüter (A)

Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran I Reynals, CIBERER U759, ISIiii, Madrid, Spain.

Baptiste Milisavljevic (B)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Benedetta Bigio (B)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Tom Le Voyer (T)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Marie Materna (M)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Adrian Gervais (A)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Marcela Moncada-Velez (M)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Francesca Pala (F)

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.

Tomi Lazarov (T)

Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Romain Levy (R)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Anna-Lena Neehus (AL)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Jérémie Rosain (J)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Jessica Peel (J)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Yi-Hao Chan (YH)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Marie-Paule Morin (MP)

Immunology and Rheumatology Division, Department of Pediatrics, University of Montreal, CHU Sainte-Justine, Montreal, QC, Canada.

Rosa Maria Pino-Ramirez (RM)

Pediatrics Department, Hospital Sant Joan de Déu, Barcelona, Spain.

Serkan Belkaya (S)

Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey.

Lazaro Lorenzo (L)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.

Jordi Anton (J)

Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
Pediatric Rheumatology Division, Hospital Sant Joan de Déu, Barcelona, Spain.
Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Institute of Recerca Sant Joan de Déu, Barcelona, Spain.

Selket Delafontaine (S)

Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium.

Julie Toubiana (J)

Department of General Pediatrics and Pediatric Infectious Diseases, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris City University, Paris, France.
Biodiversity and Epidemiology of Bacterial Pathogens, Pasteur Institute, Paris, France.

Fanny Bajolle (F)

Department of Pediatric Cardiology, Necker Hospital for Sick Children, AP-HP, Paris City University, Paris, France.

Victoria Fumadó (V)

Kids Corona Platform, Barcelona, Spain.
Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
Pediatrics Infectious Diseases Division, Hospital Sant Joan de Déu, Barcelona, Spain.
Infectious Diseases and Microbiome, Institute of Recerca Sant Joan de Déu, Barcelona, Spain.

Marta L DeDiego (ML)

Department of Molecular and Cellular Biology, National Center for Biotechnology (CNB-CSIC), Madrid, Spain.

Nadhira Fidouh (N)

Laboratory of Virology, Bichat-Claude Bernard Hospital, Paris, France.

Flore Rozenberg (F)

Laboratory of Virology, AP-HP, Cochin Hospital, Paris, France.

Jordi Pérez-Tur (J)

Molecular Genetics Unit, Institute of Biomedicine of Valencia (IBV-CSIC), Valencia, Spain.
CIBERNED, ISCIII, Madrid, Spain.
Joint Research Unit in Neurology and Molecular Genetics, Institut of Investigation Sanitaria La Fe, Valencia, Spain.

Shuibing Chen (S)

Department of Surgery, Weill Cornell Medical College, New York, NY, USA.

Todd Evans (T)

Department of Surgery, Weill Cornell Medical College, New York, NY, USA.

Frédéric Geissmann (F)

Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Pierre Lebon (P)

Medical School, Paris City University, Paris, France.

Susan R Weiss (SR)

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Damien Bonnet (D)

Department of Pediatric Cardiology, Necker Hospital for Sick Children, AP-HP, Paris City University, Paris, France.

Xavier Duval (X)

Bichat-Claude Bernard Hospital, Paris, France.
University Paris Diderot, Paris 7, UFR of Médecine-Bichat, Paris, France.
IAME, INSERM, UMRS1137, Paris City University, Paris, France.
Infectious and Tropical Diseases Department, AP-HP, Bichat-Claude Bernard Hospital, Paris, France.

Qiang Pan-Hammarström (Q)

Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.

Anna M Planas (AM)

Department of Neuroscience and Experimental Therapeutics, Institute for Biomedical Research of Barcelona (IIBB), Spanish National Research Council (CSIC), Barcelona, Spain.
Institute for Biomedical Investigations August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Isabelle Meyts (I)

Department of Pediatrics, University Hospitals Leuven and Laboratory for Inborn Errors of Immunity, KU Leuven, Leuven, Belgium.

Filomeen Haerynck (F)

Primary Immunodeficiency Research Laboratory, Center for Primary Immunodeficiency Ghent, Ghent University Hospital, Ghent, Belgium.

Aurora Pujol (A)

Neurometabolic Diseases Laboratory, IDIBELL-Hospital Duran I Reynals; and Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
CIBERER U759, ISCiii, Madrid, Spain.

Vanessa Sancho-Shimizu (V)

Department of Paediatric Infectious Diseases and Virology, Imperial College London, London, UK.
Centre for Paediatrics and Child Health, Faculty of Medicine, Imperial College London, London, UK.

Clifford L Dalgard (CL)

The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Jacinta Bustamante (J)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.
Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France.

Anne Puel (A)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Stéphanie Boisson-Dupuis (S)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Bertrand Boisson (B)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Tom Maniatis (T)

New York Genome Center, New York, NY, USA.

Qian Zhang (Q)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Paul Bastard (P)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.
Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.

Luigi Notarangelo (L)

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.

Vivien Béziat (V)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Rebeca Perez de Diego (R)

Laboratory of Immunogenetics of Human Diseases, Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz Hospital, Madrid, Spain.
Interdepartmental Group of Immunodeficiencies, Madrid, Spain.

Carlos Rodriguez-Gallego (C)

Department of Clinical Sciences, University Fernando Pessoa Canarias, Las Palmas de Gran Canaria, Spain.
Department of Immunology, University Hospital of Gran Canaria Dr. Negrín, Canarian Health System, Las Palmas de Gran Canaria, Spain.

Helen C Su (HC)

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
NIAID Clinical Genomics Program, NIH, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.

Richard P Lifton (RP)

Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Laboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY, USA.

Emmanuelle Jouanguy (E)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Aurélie Cobat (A)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Laia Alsina (L)

Kids Corona Platform, Barcelona, Spain.
Department of Surgery and Surgical Specializations, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
Study Group for Immune Dysfunction Diseases in Children (GEMDIP), Institute of Recerca Sant Joan de Déu, Barcelona, Spain.
Clinical Immunology and Primary Immunodeficiencies Unit, Pediatric Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu, Barcelona, Spain.

Sevgi Keles (S)

Necmettin Erbakan University, Konya, Turkey.

Elie Haddad (E)

Department of Pediatrics, Department of Microbiology, Immunology and Infectious Diseases, University of Montreal and Immunology and Rheumatology Division, CHU Sainte-Justine, Montreal, QC, Canada.

Laurent Abel (L)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Alexandre Belot (A)

International Center of Infectiology Research (CIRI), University of Lyon, INSERM U1111, Claude Bernard University, Lyon 1, CNRS, UMR5308, ENS of Lyon, Lyon, France.
National Reference Center for Rheumatic, Autoimmune and Systemic Diseases in Children (RAISE), Pediatric Nephrology, Rheumatology, Dermatology Unit, Hospital of Mother and Child, Hospices Civils of Lyon, Lyon, France.

Lluis Quintana-Murci (L)

Human Evolutionary Genetics Unit, Institut Pasteur, Paris City University, CNRS UMR 2000, Paris, France.
Human Genomics and Evolution, Collège de France, Paris, France.

Charles M Rice (CM)

Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.

Robert H Silverman (RH)

Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Shen-Ying Zhang (SY)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.

Jean-Laurent Casanova (JL)

St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris City University, Imagine Institute, Paris, France.
Department of Pediatrics, Necker Hospital for Sick Children, Paris, France.
Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.

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