Impact of diet on hydrogen sulfide production: implications for gut health.
Journal
Current opinion in clinical nutrition and metabolic care
ISSN: 1473-6519
Titre abrégé: Curr Opin Clin Nutr Metab Care
Pays: England
ID NLM: 9804399
Informations de publication
Date de publication:
01 01 2023
01 01 2023
Historique:
pmc-release:
01
01
2024
pubmed:
22
12
2022
medline:
24
12
2022
entrez:
21
12
2022
Statut:
ppublish
Résumé
Excessive hydrogen sulfide (H 2 S) production by the gut microbiota may contribute to the pathogenesis of multiple intestinal diseases, including colon cancer and ulcerative colitis. Therefore, understanding of dietary drivers of H 2 S production has potential implications for nutritional strategies to optimize gut health and treat intestinal diseases. Recent studies support a positive relationship between dietary protein intake and H 2 S production. However, protein rarely exists in isolation in the diet, and dietary fiber intake could reduce H 2 S production in humans and animals, even with ∼30% of calories derived from protein. These findings suggest that increased fiber intake may reduce H 2 S production irrespective of protein intake, enabling the ability to meet the metabolic demands of the illness while supporting gut health. Here we discuss two recent ulcerative colitis diet studies that illustrate this point.
Identifiants
pubmed: 36542535
doi: 10.1097/MCO.0000000000000881
pii: 00075197-202301000-00011
pmc: PMC10413438
mid: NIHMS1922128
doi:
Substances chimiques
Hydrogen Sulfide
YY9FVM7NSN
Dietary Proteins
0
Sulfides
0
Dietary Fiber
0
Types de publication
Review
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
55-58Subventions
Organisme : NCATS NIH HHS
ID : KL2 TR002530
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002529
Pays : United States
Informations de copyright
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
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