Gut microbiota and its roles in the pathogenesis and therapy of endocrine system diseases.
Fecal bacteria transplantation
Gut microbiome
Internal system diseases
Microbiology
Probiotic treatment
Journal
Microbiological research
ISSN: 1618-0623
Titre abrégé: Microbiol Res
Pays: Germany
ID NLM: 9437794
Informations de publication
Date de publication:
Mar 2023
Mar 2023
Historique:
received:
08
09
2022
accepted:
15
12
2022
pubmed:
22
12
2022
medline:
25
1
2023
entrez:
21
12
2022
Statut:
ppublish
Résumé
A new field of microbial research is the relationship between microorganisms and multicellular hosts. It is known that gut microbes can cause various endocrine system diseases, such as diabetes and thyroid disease. Changes in the composition or structure and the metabolites of gut microbes may cause gastrointestinal disorders, including ulcers or intestinal perforation and other inflammatory and autoimmune diseases. In recent years, reports on the interactions between intestinal microorganisms and endocrine system diseases have been increasingly documented. In the meantime, the treatment based on gut microbiome has also been paid much attention. For example, fecal microbiota transplantation is found to have a therapeutic effect on many diseases. As such, understanding the gut microbiota-endocrine system interactions is of great significance for the theranostic of endocrine system diseases. Herein, we summarize the relations of gut microbiome with endocrine system diseases, and discuss the potentials of regulating gut microbiome in treating those diseases. In addition, the concerns and possible solutions regarding the gut microbiome-based therapy are discussed.
Identifiants
pubmed: 36542917
pii: S0944-5013(22)00331-7
doi: 10.1016/j.micres.2022.127291
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
127291Informations de copyright
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