Hippocampus and neocortex send and receive predictive information.
Journal
Learning & behavior
ISSN: 1543-4508
Titre abrégé: Learn Behav
Pays: United States
ID NLM: 101155056
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
accepted:
09
12
2022
pmc-release:
21
06
2024
pubmed:
22
12
2022
medline:
22
12
2022
entrez:
21
12
2022
Statut:
ppublish
Résumé
A recent paper published in Nature by Yadav and colleagues (Nature 608 (7921): 153-160, 2022) illustrates a fundamental aspect on how different brain areas participate in memory storage and retrieval. After identifying neuron activity in the hippocampus CA1 region specific to multi-modal stimuli that predicted appetitive and aversive unconditioned stimuli (conjunctive stimulus encoding), the authors showed that neurons located in the anterior cingulate cortex dynamically encode the discrete sensory features of the outcome-predictive stimuli during training, and these highly specific feature-based projections can excite or inhibit conjunctive-coding neurons in the hippocampus during retrieval.
Identifiants
pubmed: 36544057
doi: 10.3758/s13420-022-00563-z
pii: 10.3758/s13420-022-00563-z
pmc: PMC10282101
mid: NIHMS1861058
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
353-354Subventions
Organisme : NIDA NIH HHS
ID : K01 DA044456
Pays : United States
Informations de copyright
© 2022. The Psychonomic Society, Inc.
Références
Holland, P. C. (1990). Event representation in Pavlovian conditioning: Image and action. Cognition, 37(1-2), 105–131. https://doi.org/10.1016/0010-0277(90)90020-K
doi: 10.1016/0010-0277(90)90020-K
pubmed: 2269004
McLaren, I. P. L., & Mackintosh, N. J. (2000). An elemental model of associative learning: I. Latent inhibition and perceptual learning. Animal Learning & Behavior, 28(3), 211–246. https://doi.org/10.3758/BF03200258
doi: 10.3758/BF03200258
Yadav, N., Noble, C., Niemeyer, J. E., Terceros, A., Victor, J., Liston, C., & Rajasethupathy, P. (2022). Prefrontal feature representations drive memory recall. Nature, 608(7921), 153–160. https://doi.org/10.1038/s41586-022-04936-2
doi: 10.1038/s41586-022-04936-2
pubmed: 35831504
pmcid: 9577479