Osteocyte lacunae in transiliac bone biopsy samples across life span.
2D-osteocyte lacunae sections (OLS)
Micropetrosis
Quantitative backscattered electron imaging (qBEI)
Transiliac bone biopsy samples
Journal
Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
received:
01
08
2022
revised:
23
11
2022
accepted:
24
11
2022
pubmed:
23
12
2022
medline:
1
2
2023
entrez:
22
12
2022
Statut:
ppublish
Résumé
Osteocytes act as bone mechanosensors, regulators of osteoblast/osteoclast activity and mineral homeostasis, however, knowledge about their functional/morphological changes throughout life is limited. We used quantitative backscattered electron imaging (qBEI) to investigate osteocyte lacunae sections (OLS) as a 2D-surrogate characterizing the osteocytes. OLS characteristics, the density of mineralized osteocyte lacunae (i.e., micropetrotic osteocytes, md.OLS-Density in nb/mm
Identifiants
pubmed: 36549635
pii: S1742-7061(22)00782-6
doi: 10.1016/j.actbio.2022.11.051
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
275-287Informations de copyright
Copyright © 2022. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: