Assessment of the Prescriptions of Systemic Antibiotics in Primary Dental Care in Germany from 2017 to 2021: A Longitudinal Drug Utilization Study.

anti-bacterial agents clindamycin dental care drug utilization insurance claims analysis primary health care

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
30 Nov 2022
Historique:
received: 09 11 2022
revised: 23 11 2022
accepted: 25 11 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 24 12 2022
Statut: epublish

Résumé

(1) Background: Due to increasing antibiotic resistance, the frequency of antibiotic use should be questioned in dentistry and attention paid to the choice of the best suited substance according to guidelines. In Germany, overprescribing of clindamycin was noteworthy in the past. Therefore, the aim of our study was to determine the trend of antibiotic prescriptions in primary dental care. (2) Methods: Prescriptions of antibiotics in German primary dental care from 2017 to 2021 were analysed using dispensing data from community pharmacies, claimed to the statutory health insurance (SHI) funds, and compared with all antibiotic prescriptions in primary care. Prescriptions were analysed based on defined daily doses per 1000 SHI-insured persons per day (DID). (3) Results: Amoxicillin was the most frequently prescribed antibiotic (0.505 DID in 2017, 0.627 in 2021, +24.2%) in primary dental care, followed by clindamycin (0.374 DID in 2017, 0.294 in 2021, -21.4%). Dental prescriptions still made up 56% of all clindamycin prescriptions in primary care in 2021. (4) Conclusions: Our study suggests that the problem of overuse of clindamycin in German dentistry has improved, but still persists.

Identifiants

pubmed: 36551380
pii: antibiotics11121723
doi: 10.3390/antibiotics11121723
pmc: PMC9774256
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Gabriele Gradl (G)

German Institute for Drug Use Evaluation (DAPI), 10557 Berlin, Germany.

Marita Kieble (M)

German Institute for Drug Use Evaluation (DAPI), 10557 Berlin, Germany.

Jens Nagaba (J)

German Dental Association (BZÄK), 10115 Berlin, Germany.

Martin Schulz (M)

German Institute for Drug Use Evaluation (DAPI), 10557 Berlin, Germany.
Department of Medicine, ABDA-Federal Union of German Associations of Pharmacists, 10557 Berlin, Germany.
Institute of Pharmacy, Freie Universität Berlin, 12169 Berlin, Germany.

Classifications MeSH