Analysis of Therapeutic Decisions for Infantile Hemangiomas: A Prospective Study Comparing the Hemangioma Severity Scale with the Infantile Hemangioma Referral Score.
Fagan nomogram
Hemangioma Severity Scale (HSS)
Infantile Hemangioma Referral Score (IHReS)
area under the curve (AUC)
receiver operating characteristic curve (ROC)
referral
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
28 Nov 2022
28 Nov 2022
Historique:
received:
06
11
2022
revised:
25
11
2022
accepted:
25
11
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
24
12
2022
Statut:
epublish
Résumé
In view of the high incidence of infantile hemangioma (IH) in infants and young children, a comprehensive and reasonable evaluation scale for referral is urgently needed. This study compared the influence of the Hemangioma Severity Scale (HSS) and the Infantile Hemangioma Referral Score (IHReS) on treatment decisions for infantile hemangioma patients. We aimed to establish a reliable and effective evaluation method for referral. This was a prospective study to determine whether treatment was needed for IH patients after evaluation with the HSS and IHReS. A total of 266 consecutive referred IH patients were evaluated for the risk of IH, and the treatment rate was 80.8%. The area under the curve (AUC) of the subject receiver operating characteristic curve (ROC) of treatment decision making after referral by the HSS was 0.703 (95% CI: 0.634-0.772), and after referral by the IHReS was 0.892 (95% CI: 0.824-0.960). This was a single-center study. For decisions regarding the treatment of IH patients, the IHReS has a higher efficiency and sensitivity than the HSS. However, the specificity of the IHReS is lower than that of the HSS.
Sections du résumé
BACKGROUND
BACKGROUND
In view of the high incidence of infantile hemangioma (IH) in infants and young children, a comprehensive and reasonable evaluation scale for referral is urgently needed. This study compared the influence of the Hemangioma Severity Scale (HSS) and the Infantile Hemangioma Referral Score (IHReS) on treatment decisions for infantile hemangioma patients.
OBJECTIVE
OBJECTIVE
We aimed to establish a reliable and effective evaluation method for referral.
METHODS
METHODS
This was a prospective study to determine whether treatment was needed for IH patients after evaluation with the HSS and IHReS.
RESULTS
RESULTS
A total of 266 consecutive referred IH patients were evaluated for the risk of IH, and the treatment rate was 80.8%. The area under the curve (AUC) of the subject receiver operating characteristic curve (ROC) of treatment decision making after referral by the HSS was 0.703 (95% CI: 0.634-0.772), and after referral by the IHReS was 0.892 (95% CI: 0.824-0.960).
LIMITATIONS
CONCLUSIONS
This was a single-center study.
CONCLUSIONS
CONCLUSIONS
For decisions regarding the treatment of IH patients, the IHReS has a higher efficiency and sensitivity than the HSS. However, the specificity of the IHReS is lower than that of the HSS.
Identifiants
pubmed: 36553295
pii: children9121851
doi: 10.3390/children9121851
pmc: PMC9777170
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : National Natural Science Foundation of China
ID : 82273556
Organisme : the Key Project in the Science & Technology Program of Sichuan Province
ID : 2022YFS0233
Organisme : the Key Project in the Science & Technology Program of Sichuan Province
ID : 2022YFS0225
Organisme : the Key Project in the Science & Technology Program of Sichuan Province
ID : 2019YFS0322
Organisme : the Project of '0 to 1' of Sichuan University
ID : 2022SCUH0033
Organisme : Med-X Center for Informatics Funding Project
ID : YGJC004
Organisme : the 1·3·5 Project for Disciplines of Excellence Clinical Research Incubation Project, West China Hospital of Sichuan University
ID : ZYJC21060
Organisme : the 1·3·5 Project for Disciplines of Excellence Clinical Research Incubation Project, West China Hospital of Sichuan University
ID : 2020HXFH048
Organisme : the 1·3·5 Project for Disciplines of Excellence Clinical Research Incubation Project, West China Hospital of Sichuan University
ID : 2019HXFH056
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