Calibration of Methods for SARS-CoV-2 Environmental Surveillance: A Case Study from Northwest Tuscany.

HCoV-229E SARS-CoV-2 mengovirus VMC0 wastewater surveillance wastewater-based epidemiology

Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
09 12 2022
Historique:
received: 01 11 2022
revised: 02 12 2022
accepted: 05 12 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 27 12 2022
Statut: epublish

Résumé

The current pandemic has provided an opportunity to test wastewater-based epidemiology (WBE) as a complementary method to SARS-CoV-2 monitoring in the community. However, WBE infection estimates can be affected by uncertainty factors, such as heterogeneity in analytical procedure, wastewater volume, and population size. In this paper, raw sewage SARS-CoV-2 samples were collected from four wastewater treatment plants (WWTPs) in Tuscany (Northwest Italy) between February and December 2021. During the surveillance period, viral concentration was based on polyethylene glycol (PEG), but its precipitation method was modified from biphasic separation to centrifugation. Therefore, in parallel, the recovery efficiency of each method was evaluated at lab-scale, using two spiking viruses (human coronavirus 229E and mengovirus vMC

Identifiants

pubmed: 36554466
pii: ijerph192416588
doi: 10.3390/ijerph192416588
pmc: PMC9778686
pii:
doi:

Substances chimiques

Sewage 0
RNA, Viral 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

The authors declare no conflicts of interest. The companies had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Marco Verani (M)

Laboratory of Hygiene and Environmental Virology, Department of Biology, University of Pisa, Via S. Zeno 35/39, 56127 Pisa, Italy.

Ileana Federigi (I)

Laboratory of Hygiene and Environmental Virology, Department of Biology, University of Pisa, Via S. Zeno 35/39, 56127 Pisa, Italy.

Sara Muzio (S)

Laboratory of Hygiene and Environmental Virology, Department of Biology, University of Pisa, Via S. Zeno 35/39, 56127 Pisa, Italy.

Giulia Lauretani (G)

Laboratory of Hygiene and Environmental Virology, Department of Biology, University of Pisa, Via S. Zeno 35/39, 56127 Pisa, Italy.

Piergiuseppe Calà (P)

Tuscany Region-Health, Department of Prevention Local Health Authority Tuscany Center, Via S. Salvi 12, 50135 Firenze, Italy.

Fabrizio Mancuso (F)

Ingegnerie Toscane-Area R&D, Via Bellatalla 1, 56121 Pisa, Italy.

Roberto Salvadori (R)

Acque S.p.A., Via A. Bellatalla 1, 56121 Pisa, Italy.

Claudia Valentini (C)

Gaia S.p.A., Via Donizetti 16, 55045 Pietrasanta, Italy.

Giuseppina La Rosa (G)

Department of Environment and Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

Elisabetta Suffredini (E)

Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

Annalaura Carducci (A)

Laboratory of Hygiene and Environmental Virology, Department of Biology, University of Pisa, Via S. Zeno 35/39, 56127 Pisa, Italy.

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Classifications MeSH