Contrast Agents during Pregnancy: Pros and Cons When Really Needed.

computerized tomography contrast media ionizing radiation magnetic resonance imaging positron emission tomography pregnant radiodiagnostic ultrasound

Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
12 12 2022
Historique:
received: 14 10 2022
revised: 06 12 2022
accepted: 10 12 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 27 12 2022
Statut: epublish

Résumé

Many clinical conditions require radiological diagnostic exams based on the emission of different kinds of energy and the use of contrast agents, such as computerized tomography (CT), positron emission tomography (PET), magnetic resonance (MR), ultrasound (US), and X-ray imaging. Pregnant patients who should be submitted for diagnostic examinations with contrast agents represent a group of patients with whom it is necessary to consider both maternal and fetal effects. Radiological examinations use different types of contrast media, the most used and studied are represented by iodinate contrast agents, gadolinium, fluorodeoxyglucose, gastrographin, bariumsulfate, and nanobubbles used in contrast-enhanced ultrasound (CEUS). The present paper reports the available data about each contrast agent and its effect related to the mother and fetus. This review aims to clarify the clinical practices to follow in cases where a radiodiagnostic examination with a contrast medium is indicated to be performed on a pregnant patient.

Identifiants

pubmed: 36554582
pii: ijerph192416699
doi: 10.3390/ijerph192416699
pmc: PMC9779218
pii:
doi:

Substances chimiques

Contrast Media 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Federica Perelli (F)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.

Irene Turrini (I)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.

Maria Gabriella Giorgi (MG)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.

Irene Renda (I)

Division of Obstetrics and Gynecology, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, 50134 Florence, Italy.

Annalisa Vidiri (A)

School of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.

Gianluca Straface (G)

Obstetrics and Gynecology Unit, Policlinico Abano Terme, 35031 Abano Terme, Italy.

Elisa Scatena (E)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.

Marco D'Indinosante (M)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.

Laura Marchi (L)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santo Stefano Hospital, 59100 Prato, Italy.

Marco Giusti (M)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.

Antonio Oliva (A)

Department of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Simone Grassi (S)

Department of Health Surveillance and Bioethics, Section of Legal Medicine, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.

Carmen De Luca (C)

Teratology Information Service, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

Francesco Catania (F)

Department of Obstetrics and Gynecology, Ospedale "Santa Maria Alla Gruccia", 52025 Montevarchi, Italy.

Giuseppe Vizzielli (G)

Department of Medicinal Area (DAME) Clinic of Obstetrics and Gynecology, Santa Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.

Stefano Restaino (S)

Department of Medicinal Area (DAME) Clinic of Obstetrics and Gynecology, Santa Maria della Misericordia Hospital, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.

Giuseppe Gullo (G)

IVF Public Center, Azienda Ospedaliera Ospedali Riuniti (AOOR) Villa Sofia Cervello, University of Palermo, 90146 Palermo, Italy.

Georgios Eleftheriou (G)

Poison Control Center and Teratology Information Service, Hospital Papa Giovanni XIII, 24127 Bergamo, Italy.

Alberto Mattei (A)

Azienda USL Toscana Centro, Gynecology and Obstetric Department, Santa Maria Annunziata Hospital, 50012 Florence, Italy.

Fabrizio Signore (F)

Obstetrics and Gynecology Unit, Santo Eugenio Hospital, 00144 Rome, Italy.
School of Medicine, Unicamillus University Rome, 00131 Rome, Italy.

Antonio Lanzone (A)

School of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

Giovanni Scambia (G)

School of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Division of Gynecologic Oncology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.

Anna Franca Cavaliere (AF)

School of Medicine, Catholic University of the Sacred Hearth, 00168 Rome, Italy.
Division of Gynecology and Obstetrics Fatebenefratelli Isola Tiberina, 00186 Rome, Italy.

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