A Dietary Supplement Containing Fucoidan Preserves Endothelial Glycocalyx through ERK/MAPK Signaling and Protects against Damage Induced by CKD Serum.
ERK/MAPK signaling
chronic kidney disease
endocalyx
endothelial activation
fucoidan
glycocalyx
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
08 Dec 2022
08 Dec 2022
Historique:
received:
29
10
2022
revised:
28
11
2022
accepted:
05
12
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
27
12
2022
Statut:
epublish
Résumé
(1) Damage to the endothelial glycocalyx (eGC), a protective layer lining the endothelial luminal surface, is associated with chronic kidney disease (CKD), which leads to a worsening of cardiovascular outcomes in these patients. Currently, there are no targeted therapeutic approaches. Whether the dietary supplement Endocalyx
Identifiants
pubmed: 36555160
pii: ijms232415520
doi: 10.3390/ijms232415520
pmc: PMC9779516
pii:
doi:
Substances chimiques
fucoidan
9072-19-9
Phosphatidylinositol 3-Kinases
EC 2.7.1.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : German Research Foundation
ID : KFO 342-ZA428/18-1
Organisme : German Research Foundation
ID : KU 2873/3-1
Organisme : fund Innovative Medical Research of the University of Münster Medical School
ID : I-RO221907
Organisme : Else Kröner-Fresenius-Stiftung
ID : 2018_A134
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