Biventricular Arrhythmogenic Cardiomyopathy Associated with a Novel Heterozygous

arrhythmogenic cardiomyopathy exercise plakophilin-2

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
19 Dec 2022
Historique:
received: 22 11 2022
revised: 14 12 2022
accepted: 15 12 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 24 12 2022
Statut: epublish

Résumé

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is a hereditary condition that can cause sudden cardiac death in young, frequently athletic individuals under the age of 35 due to malignant arrhythmias. Competitive and endurance exercise may hasten the onset and progression of ARVC, leading to right ventricular dysfunction and potentially fatal ventricular arrhythmias earlier in life. In this article, we present a novel, pathogenic, early truncating heterozygous variant in the

Identifiants

pubmed: 36556128
pii: jcm11247513
doi: 10.3390/jcm11247513
pmc: PMC9782591
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Tolga Çimen (T)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Verena C Wilzeck (VC)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Giulia Montrasio (G)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Nicole R Bonetti (NR)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Argelia Medeiros-Domingo (A)

Swiss DNAlysis, 8600 Dubendorf, Switzerland.

Christian Grebmer (C)

Department of Cardiology, Luzerner Kantonsspital, 6000 Lucerne, Switzerland.

Christian M Matter (CM)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Felix C Tanner (FC)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Robert Manka (R)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Corinna B Brunckhorst (CB)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Firat Duru (F)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.
Center for Integrative Human Physiology, University of Zurich, 8091 Zurich, Switzerland.

Ardan M Saguner (AM)

Department of Cardiology, University Heart Center, University Hospital Zurich, 8091 Zurich, Switzerland.

Classifications MeSH