Axial Spondyloarthritis: Reshape the Future-From the "2022 GISEA International Symposium".
axial spondyloarthritis
pain
pathogenesis
therapy
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
19 Dec 2022
19 Dec 2022
Historique:
received:
20
10
2022
revised:
02
12
2022
accepted:
15
12
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
24
12
2022
Statut:
epublish
Résumé
The term "axial spondyloarthritis" (axSpA) refers to a group of chronic rheumatic diseases that predominantly involve the axial skeleton and consist of ankylosing spondylitis, reactive arthritis, arthritis/spondylitis associated with psoriasis (PsA) and arthritis/spondylitis associated with inflammatory bowel diseases (IBD). Moreover, pain is an important and common symptom of axSpA. It may progress to chronic pain, a more complicated bio-psychosocial phenomena, leading to a significant worsening of quality of life. The development of the axSpA inflammatory process is grounded in the complex interaction between genetic (such as HLA B27), epigenetic, and environmental factors associated with a dysregulated immune response. Considering the pivotal contribution of IL-23 and IL-17 in axSpA inflammation, the inhibition of these cytokines has been evaluated as a potential therapeutic strategy. With this context, here we discuss the main pathogenetic mechanisms, therapeutic approaches and the role of pain in axSpA from the 2022 International GISEA/OEG Symposium.
Identifiants
pubmed: 36556152
pii: jcm11247537
doi: 10.3390/jcm11247537
pmc: PMC9780899
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Reumatismo. 2014 Jun 06;66(1):28-32
pubmed: 24938193
Ann Rheum Dis. 2017 Jun;76(6):1123-1132
pubmed: 28069576
Expert Opin Biol Ther. 2022 Jul;22(7):843-853
pubmed: 35722768
Arthritis Rheumatol. 2015 Mar;67(3):686-691
pubmed: 25417597
Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 107(5):102-107
pubmed: 28967358
Arthritis Rheum. 2005 Nov;52(11):3586-95
pubmed: 16255049
Ann Rheum Dis. 2014 Feb;73(2):437-45
pubmed: 23921997
J Am Acad Dermatol. 2018 Jan;78(1):81-89.e5
pubmed: 28985956
Mol Med Rep. 2017 Apr;15(4):1943-1951
pubmed: 28259985
Arthritis Rheumatol. 2021 Jan;73(1):110-120
pubmed: 32770640
Inflamm Bowel Dis. 2013 Jul;19(8):1567-76
pubmed: 23689808
Pain Physician. 2014 Sep-Oct;17(5):447-57
pubmed: 25247901
Blood. 2014 Jul 31;124(5):700-9
pubmed: 24778151
Arthritis Rheumatol. 2019 Oct;71(10):1599-1613
pubmed: 31436036
Immunotargets Ther. 2021 May 03;10:141-153
pubmed: 33977094
N Engl J Med. 2012 Mar 29;366(13):1181-9
pubmed: 22455412
Ann Rheum Dis. 2014 May;73(5):817-23
pubmed: 24389297
Ann Rheum Dis. 2016 Nov;75(11):1984-1988
pubmed: 27098404
Rheumatol Int. 2014 Aug;34(8):1103-10
pubmed: 24509896
Clin Rheumatol. 2020 Jan;39(1):269-274
pubmed: 31446538
Nat Commun. 2015 May 21;6:7146
pubmed: 25994336
Mod Rheumatol. 2020 Jan;30(1):132-140
pubmed: 30334633
Ann Rheum Dis. 2020 Feb;79(2):202-208
pubmed: 31662321
Psychol Bull. 2007 Jul;133(4):581-624
pubmed: 17592957
Immunology. 2012 Feb;135(2):112-24
pubmed: 22044352
Ann Rheum Dis. 2020 May;79(5):595-604
pubmed: 32253184
Pain. 2011 Oct;152(10):2204-2205
pubmed: 21764514
Nat Immunol. 2017 May 18;18(6):604-611
pubmed: 28518154
Lancet. 2013 Nov 23;382(9906):1705-13
pubmed: 24035250
Arthritis Rheum. 2013 Jun;65(6):1494-503
pubmed: 23460087
Anesthesiology. 2018 Aug;129(2):343-366
pubmed: 29462012
N Engl J Med. 2015 Dec 24;373(26):2534-48
pubmed: 26699169
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):1272-1281
pubmed: 34842133
J Clin Immunol. 2013 Jan;33(1):151-61
pubmed: 22926407
Arthritis Rheum. 2009 Sep;60(9):2633-43
pubmed: 19714651
Mayo Clin Proc. 2022 Jan;97(1):134-145
pubmed: 34801248
J Immunol. 2006 Jan 15;176(2):1098-106
pubmed: 16393998
World Neurosurg. 2017 Aug;104:594-600
pubmed: 28479522
Arthritis Rheum. 2009 Apr;60(4):955-65
pubmed: 19333939
RMD Open. 2020 Sep;6(3):
pubmed: 32950963
Rheumatol Ther. 2018 Dec;5(2):447-462
pubmed: 30121827
Arthritis Res Ther. 2014 Aug 22;16(4):426
pubmed: 25146432
Front Immunol. 2021 Feb 18;11:623874
pubmed: 33679714
J Clin Rheumatol. 2018 Sep;24(6):324-327
pubmed: 29708517
Arthritis Res Ther. 2016 Jun 23;18:148
pubmed: 27338729
BioDrugs. 2020 Oct;34(5):669-679
pubmed: 32946076
Arthritis Rheumatol. 2014 Nov;66(11):2976-88
pubmed: 25132672
Arthritis Rheum. 2013 Jan;65(1):174-85
pubmed: 22972410
Rheumatology (Oxford). 2016 Nov;55(11):2014-2022
pubmed: 27520798
Knee Surg Sports Traumatol Arthrosc. 2018 Nov;26(11):3419-3428
pubmed: 29574545
Bone Res. 2019 Aug 5;7:22
pubmed: 31666997
Expert Opin Biol Ther. 2016;16(5):711-22
pubmed: 26982813
Immunol Lett. 2016 Oct;178:20-6
pubmed: 27173097
Lancet. 2018 Dec 8;392(10163):2441-2451
pubmed: 30360964
J Autoimmun. 2018 Feb;87:1-15
pubmed: 29275836
Expert Opin Biol Ther. 2020 Jul;20(7):813-821
pubmed: 32401062
Arthritis Rheumatol. 2019 Feb;71(2):258-270
pubmed: 30225992
Clin Immunol. 2019 Sep;206:15-22
pubmed: 30196070
Semin Arthritis Rheum. 2016 Dec;46(3):319-329
pubmed: 27916278
Arthritis Res Ther. 2017 Dec 22;19(1):285
pubmed: 29273067
Clin Exp Rheumatol. 2011 Sep-Oct;29(5):828-34
pubmed: 22041179
Ann Rheum Dis. 2018 Sep;77(9):1295-1302
pubmed: 29945918
RMD Open. 2020 Feb;6(1):
pubmed: 32209721
Rheumatology (Oxford). 2021 Oct 2;60(10):4476-4485
pubmed: 33492397
J Chin Med Assoc. 2012 Jul;75(7):303-8
pubmed: 22824043
Pain. 2008 Jul 31;137(3):473-477
pubmed: 18583048
Nat Rev Rheumatol. 2018 Aug;14(8):453-466
pubmed: 30006601
PLoS One. 2017 Jul 7;12(7):e0180014
pubmed: 28686639
Pain Pract. 2022 Nov;22(8):702-710
pubmed: 36097821
Scand J Psychol. 2020 Apr;61(2):271-280
pubmed: 31674683
Ann Rheum Dis. 2017 Mar;76(3):571-592
pubmed: 27582421
Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1283-90
pubmed: 16684953
Rheumatology (Oxford). 2018 Sep 1;57(9):1541-1547
pubmed: 28968885
Clin Exp Rheumatol. 2020 Jan-Feb;38(1):27-34
pubmed: 31025924
Nat Immunol. 2002 Dec;3(12):1177-84
pubmed: 12436110
Ann Rheum Dis. 2018 Apr;77(4):523-532
pubmed: 29275332
Ann Rheum Dis. 2021 Aug;80(8):1014-1021
pubmed: 33827787
Nat Immunol. 2017 Jan;18(1):104-113
pubmed: 27820809
Ann Rheum Dis. 2022 Apr;81(4):466-468
pubmed: 34656991
Clin Exp Immunol. 2016 Oct;186(1):64-74
pubmed: 27328392
Clin Rheumatol. 2018 Nov;37(11):3077-3086
pubmed: 29713968
Joint Bone Spine. 2007 May;74(3):304-5
pubmed: 17369068
Front Cell Neurosci. 2018 Feb 13;12:35
pubmed: 29487504
Arthritis Rheumatol. 2019 Apr;71(4):599-611
pubmed: 30343531