Thymoquinone: Hydroxypropyl-β-cyclodextrin Loaded Bacterial Cellulose for the Management of Wounds.
anti-fungal
bacterial cellulose
biomaterials
biopolymer
controlled drug release
experimental dermatology
wound dressing
Journal
Pharmaceutics
ISSN: 1999-4923
Titre abrégé: Pharmaceutics
Pays: Switzerland
ID NLM: 101534003
Informations de publication
Date de publication:
15 Dec 2022
15 Dec 2022
Historique:
received:
16
10
2022
revised:
23
11
2022
accepted:
13
12
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
24
12
2022
Statut:
epublish
Résumé
The need for more advantageous and pharmaceutically active wound dressings is a pressing matter in the area of wound management. In this study, we explore the possibility of incorporating thymoquinone within bacterial cellulose, utilising cyclodextrins as a novel method of solubilising hydrophobic compounds. The thymoquinone was not soluble in water, so was incorporated within hydroxypropyl-β-cyclodextrin before use. Thymoquinone: hydroxypropyl-β-cyclodextrin inclusion complex produced was found to be soluble in water up to 7% (
Identifiants
pubmed: 36559309
pii: pharmaceutics14122816
doi: 10.3390/pharmaceutics14122816
pmc: PMC9781873
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Drug Deliv Transl Res. 2023 Jan;13(1):292-307
pubmed: 35831776
Prog Biomater. 2018 Mar;7(1):1-21
pubmed: 29446015
Pharmaceutics. 2022 Jan 16;14(1):
pubmed: 35057101
Curr Pharm Biotechnol. 2020;21(11):1028-1041
pubmed: 32297580
Microb Biotechnol. 2019 Jul;12(4):586-610
pubmed: 30838788
Biomed Pharmacother. 2022 May;149:112862
pubmed: 35339826
Biotechnol Bioeng. 2019 Dec;116(12):3372-3381
pubmed: 31433066
Molecules. 2018 Sep 18;23(9):
pubmed: 30231567
Pharmaceuticals (Basel). 2022 Mar 27;15(4):
pubmed: 35455405
Life (Basel). 2022 Sep 15;12(9):
pubmed: 36143470
Polymers (Basel). 2021 Jan 28;13(3):
pubmed: 33525406
Surg Clin North Am. 2020 Aug;100(4):757-776
pubmed: 32681875
Front Pharmacol. 2017 Sep 21;8:656
pubmed: 28983249
Curr Drug Targets. 2019;20(8):808-822
pubmed: 30488795
AAPS PharmSciTech. 2004 Feb 19;5(2):e28
pubmed: 15760086
Stem Cell Res Ther. 2019 Mar 15;10(1):94
pubmed: 30876456
Biomacromolecules. 2020 May 11;21(5):1802-1811
pubmed: 31967794
Virology. 2021 Sep;561:36-46
pubmed: 34146962
Pharmaceutics. 2022 May 15;14(5):
pubmed: 35631645
Molecules. 2021 Jun 24;26(13):
pubmed: 34202733
Recent Pat Drug Deliv Formul. 2018;12(1):3-22
pubmed: 29189187
Mater Sci Eng C Mater Biol Appl. 2017 Jul 1;76:319-329
pubmed: 28482534
J Biol Eng. 2019 Jun 20;13:55
pubmed: 31249615
Bioprocess Biosyst Eng. 2020 May;43(5):927-936
pubmed: 31997008
Int J Biol Macromol. 2019 Jun 15;131:230-240
pubmed: 30872059
Infect Dis Ther. 2020 Mar;9(1):1-15
pubmed: 32072492
Phytochemistry. 2022 Aug;200:113213
pubmed: 35472482
Polymers (Basel). 2019 Jul 04;11(7):
pubmed: 31277438
Materials (Basel). 2021 May 18;14(10):
pubmed: 34070218
Artif Cells Nanomed Biotechnol. 2017 May;45(3):591-597
pubmed: 28211300
Adv Wound Care (New Rochelle). 2014 Aug 1;3(8):511-529
pubmed: 25126472
Drug Discov Today. 2021 Nov;26(11):2716-2725
pubmed: 34303824
Eur J Pharm Sci. 2019 May 15;133:167-182
pubmed: 30902654
RSC Adv. 2022 Jan 12;12(4):1982-1988
pubmed: 35425234
Molecules. 2022 Oct 10;27(19):
pubmed: 36235288