Diarrhea Is a Hallmark of Inflammation in Pediatric COVID-19.
COVID-19
SARS-CoV-2
children
diarrhea
gastrointestinal
gut
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
06 12 2022
06 12 2022
Historique:
received:
13
10
2022
revised:
28
11
2022
accepted:
04
12
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
27
12
2022
Statut:
epublish
Résumé
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pathogen with enteric tropism. We compared the clinical, biochemical and radiological features of children hospitalized for acute SARS-CoV-2 infection, classified in two groups based on the presence of diarrhea. Logistic regression analyses were used to investigate the variables associated with diarrhea. Overall, 407 children were included in the study (226 males, 55.5%, mean age 3.9 ± 5.0 years), of whom 77 (18.9%) presented with diarrhea, which was mild in most cases. Diarrhea prevalence was higher during the Alpha (23.6%) and Delta waves (21.9%), and in children aged 5-11 y (23.8%). Other gastrointestinal symptoms were most commonly reported in children with diarrhea (
Identifiants
pubmed: 36560726
pii: v14122723
doi: 10.3390/v14122723
pmc: PMC9783993
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Lancet Gastroenterol Hepatol. 2020 Apr;5(4):335-337
pubmed: 32087098
J Clin Med. 2022 Jul 25;11(15):
pubmed: 35893395
Front Pediatr. 2021 Mar 16;9:649358
pubmed: 33796491
Front Pediatr. 2022 Jul 15;10:904793
pubmed: 35911826
Front Med (Lausanne). 2021 Jun 04;8:671714
pubmed: 34150807
Heliyon. 2022 Aug;8(8):e10246
pubmed: 35996551
Medicine (Baltimore). 2021 Oct 15;100(41):e27528
pubmed: 34731146
JAMA Netw Open. 2021 Dec 1;4(12):e2139974
pubmed: 34928354
Cell Rep. 2022 Apr 26;39(4):110729
pubmed: 35452593
J Pediatr Gastroenterol Nutr. 2021 Sep 1;73(3):299-305
pubmed: 34117195
Children (Basel). 2022 Jul 14;9(7):
pubmed: 35884027
Nat Immunol. 2022 Feb;23(2):177-185
pubmed: 35105983
Intest Res. 2021 Oct;19(4):379-385
pubmed: 33142370
J Glob Health. 2021 Dec 25;11:01010
pubmed: 35047182
Pediatrics. 2022 Apr 1;149(4):
pubmed: 35322270
Sci Rep. 2021 Nov 5;11(1):21725
pubmed: 34741071
Front Biosci (Schol Ed). 2022 Aug 3;14(3):23
pubmed: 36137978
Front Pediatr. 2021 Feb 22;9:617980
pubmed: 33692973
Med Hypotheses. 2020 Nov;144:110023
pubmed: 32593832
Clin Chem Lab Med. 2021 May 13;:
pubmed: 33984877
Nat Rev Microbiol. 2019 Mar;17(3):181-192
pubmed: 30531947
JAMA Netw Open. 2021 Apr 1;4(4):e215298
pubmed: 33835179
Sci Rep. 2022 Apr 27;12(1):6843
pubmed: 35478198
Front Cell Infect Microbiol. 2022 Jul 08;12:908492
pubmed: 35873161
Dig Dis Sci. 2022 Aug;67(8):3860-3871
pubmed: 34751837
Pediatr Infect Dis J. 2022 May 1;41(5):e249-e251
pubmed: 35333818
J Pediatr Gastroenterol Nutr. 2014 Jul;59(1):132-52
pubmed: 24739189
Virol J. 2022 Apr 26;19(1):76
pubmed: 35473640
Medicine (Baltimore). 2022 Jun 24;101(25):e29374
pubmed: 35758370
Br J Radiol. 2022 Aug 1;95(1136):20220101
pubmed: 35762341