Electrospun hybrid nanofibers: Fabrication, characterization, and biomedical applications.

biomedical applications characterization electrospinning hybrid nanofibers wound healing

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2022
Historique:
received: 05 07 2022
accepted: 16 11 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 24 12 2022
Statut: epublish

Résumé

Nanotechnology is one of the most promising technologies available today, holding tremendous potential for biomedical and healthcare applications. In this field, there is an increasing interest in the use of polymeric micro/nanofibers for the construction of biomedical structures. Due to its potential applications in various fields like pharmaceutics and biomedicine, the electrospinning process has gained considerable attention for producing nano-sized fibers. Electrospun nanofiber membranes have been used in drug delivery, controlled drug release, regenerative medicine, tissue engineering, biosensing, stent coating, implants, cosmetics, facial masks, and theranostics. Various natural and synthetic polymers have been successfully electrospun into ultrafine fibers. Although biopolymers demonstrate exciting properties such as good biocompatibility, non-toxicity, and biodegradability, they possess poor mechanical properties. Hybrid nanofibers from bio and synthetic nanofibers combine the characteristics of biopolymers with those of synthetic polymers, such as high mechanical strength and stability. In addition, a variety of functional agents, such as nanoparticles and biomolecules, can be incorporated into nanofibers to create multifunctional hybrid nanofibers. Due to the remarkable properties of hybrid nanofibers, the latest research on the unique properties of hybrid nanofibers is highlighted in this study. Moreover, various established hybrid nanofiber fabrication techniques, especially the electrospinning-based methods, as well as emerging strategies for the characterization of hybrid nanofibers, are summarized. Finally, the development and application of electrospun hybrid nanofibers in biomedical applications are discussed.

Identifiants

pubmed: 36561047
doi: 10.3389/fbioe.2022.986975
pii: 986975
pmc: PMC9764016
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

986975

Informations de copyright

Copyright © 2022 Abadi, Goshtasbi, Bolourian, Tahsili, Adeli-Sardou and Forootanfar.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Banafshe Abadi (B)

Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Brain Cancer Research Core (BCRC), Universal Scientific Education and Research Network (USERN), Kerman, Iran.

Nazanin Goshtasbi (N)

Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Saman Bolourian (S)

Department of Biology, Faculty of Science, Alzahra University, Tehran, Iran.

Jaleh Tahsili (J)

Department of Plant Biology, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran.

Mahboubeh Adeli-Sardou (M)

Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

Hamid Forootanfar (H)

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.

Classifications MeSH