The prevention and treatment of breast cancer- related lymphedema: A review.
LyMPHA
axillary reverse mapping
axillary surgery
breast cancer
breast cancer related lymphedema
lymphedema
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
05
10
2022
accepted:
07
11
2022
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
24
12
2022
Statut:
epublish
Résumé
Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed. The American Society of Breast Surgeons Lymphatic Surgery Working Group conducted a large review of the literature in order to develop guidelines on BCRL prevention and treatment. This was a comprehensive but not systematic review of the literature. This was inclusive of recent randomized controlled trials, meta-analyses, and reviews evaluating the prevention and treatment of BCRL. There were 25 randomized clinical trials, 13 systemic reviews and meta-analyses, and 87 observational studies included. The findings of our review are detailed in the paper, with each guideline being analyzed with the most recent data that the group found evidence of to suggest these recommendations. Prevention and treatment of BCRL involve a multidisciplinary team. Early detection, before clinically apparent, is crucial to prevent irreversible lymphedema. Awareness of risk factors and appropriate practice adjustments to reduce the risk aids are crucial to decrease the progression of lymphedema. The treatment can be costly, time- consuming, and not always effective, and therefore, the overall goal should be prevention.
Sections du résumé
Background
UNASSIGNED
Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed.
Methods
UNASSIGNED
The American Society of Breast Surgeons Lymphatic Surgery Working Group conducted a large review of the literature in order to develop guidelines on BCRL prevention and treatment. This was a comprehensive but not systematic review of the literature. This was inclusive of recent randomized controlled trials, meta-analyses, and reviews evaluating the prevention and treatment of BCRL. There were 25 randomized clinical trials, 13 systemic reviews and meta-analyses, and 87 observational studies included.
Results
UNASSIGNED
The findings of our review are detailed in the paper, with each guideline being analyzed with the most recent data that the group found evidence of to suggest these recommendations.
Conclusions
UNASSIGNED
Prevention and treatment of BCRL involve a multidisciplinary team. Early detection, before clinically apparent, is crucial to prevent irreversible lymphedema. Awareness of risk factors and appropriate practice adjustments to reduce the risk aids are crucial to decrease the progression of lymphedema. The treatment can be costly, time- consuming, and not always effective, and therefore, the overall goal should be prevention.
Identifiants
pubmed: 36561522
doi: 10.3389/fonc.2022.1062472
pmc: PMC9763870
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1062472Informations de copyright
Copyright © 2022 McEvoy, Gomberawalla, Smith, Boccardo, Holmes, Djohan, Thiruchelvam, Klimberg, Dietz and Feldman.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Surg Gynecol Obstet. 1970 Jul;131(1):79-88
pubmed: 5419966
Lymphology. 2001 Mar;34(1):2-11
pubmed: 11307661
Ann Surg Oncol. 2017 Oct;24(10):2827-2835
pubmed: 28766218
Front Mol Biosci. 2022 Sep 08;9:930361
pubmed: 36158576
Microsurgery. 2022 Jul;42(5):433-440
pubmed: 34994481
Minerva Ginecol. 2012 Oct;64(5):421-30
pubmed: 23018481
BMJ. 2010 Jan 12;340:b5396
pubmed: 20068255
JAMA. 2017 Sep 12;318(10):918-926
pubmed: 28898379
JAMA Surg. 2015 Feb;150(2):137-43
pubmed: 25517573
Am J Surg. 2009 Oct;198(4):482-7
pubmed: 19800452
Ann Surg Oncol. 2013 Mar;20(3):842-9
pubmed: 23054109
Breast Cancer Res Treat. 2017 Apr;162(2):219-224
pubmed: 28083821
Plast Reconstr Surg. 2013 Nov;132(5):1305-1314
pubmed: 24165613
Ann Surg Oncol. 2017 Oct;24(10):2818-2826
pubmed: 28766232
Eur J Surg Oncol. 2020 Jun;46(6):1041-1045
pubmed: 31801656
Ann Surg. 2012 Mar;255(3):468-73
pubmed: 22233832
N Engl J Med. 2009 Aug 13;361(7):664-73
pubmed: 19675330
Breast Cancer Res Treat. 2017 Apr;162(2):201-215
pubmed: 28012086
Lancet Oncol. 2013 May;14(6):500-15
pubmed: 23540561
Ann Surg Oncol. 2021 Aug;28(8):4277-4283
pubmed: 33417121
Ann Surg Oncol. 2011 Sep;18(9):2500-5
pubmed: 21369739
Breast Cancer Res Treat. 2015 May;151(1):121-9
pubmed: 25850535
Breast J. 2019 Nov;25(6):1323-1325
pubmed: 31518487
Scand J Plast Reconstr Surg. 1986;20(1):141-6
pubmed: 3775285
Int J Radiat Oncol Biol Phys. 2014 Mar 1;88(3):565-71
pubmed: 24411624
Acta Oncol. 2009;48(8):1102-10
pubmed: 19863217
J Clin Oncol. 2015 Jan 20;33(3):258-64
pubmed: 25452445
Ann Surg. 2017 May;265(5):987-992
pubmed: 27163955
J Clin Oncol. 2003 Mar 15;21(6):976-83
pubmed: 12637460
J Pers Med. 2014 Aug 18;4(3):424-47
pubmed: 25563360
Plast Reconstr Surg. 2014 Feb;133(2):192e-198e
pubmed: 24469190
N Engl J Med. 2010 Dec 2;363(23):2200-10
pubmed: 21121833
Lymphology. 2016 Dec;49(4):170-84
pubmed: 29908550
Gland Surg. 2021 Apr;10(4):1447-1459
pubmed: 33968696
J Clin Oncol. 2016 Apr 1;34(10):1072-8
pubmed: 26811528
Breast J. 2018 Jan;24(1):62-65
pubmed: 29063664
Front Oncol. 2016 Sep 05;6:192
pubmed: 27656420
Ann Surg. 2019 Dec;270(6):1156-1160
pubmed: 29794843
Ann Surg Oncol. 2011 Jan;18(1):125-33
pubmed: 20652755
Br J Surg. 2016 Feb;103(3):170-8
pubmed: 26661686
Lymphat Res Biol. 2014 Dec;12(4):289-94
pubmed: 25495384
Breast J. 2012 Jul-Aug;18(4):357-61
pubmed: 22759095
Eur J Cancer Care (Engl). 1998 Jun;7(2):97-8
pubmed: 9697450
Breast Cancer Res Treat. 2019 Jan;173(2):343-352
pubmed: 30343457
Eur J Obstet Gynecol Reprod Biol. 2016 May;200:117-22
pubmed: 27019287
Ann Surg Oncol. 2009 Jul;16(7):1959-72
pubmed: 19365624
J Reconstr Microsurg. 2016 Jan;32(1):34-41
pubmed: 26165882
Ann Plast Surg. 2019 Apr;82(4S Suppl 3):S234-S241
pubmed: 30855393
Breast. 2020 Oct;53:189-200
pubmed: 32858404
J Clin Oncol. 2014 Nov 10;32(32):3600-6
pubmed: 25135994
J Surg Oncol. 2008 Jun 1;97(7):563-4
pubmed: 17955452
Eur J Surg Oncol. 2011 Dec;37(12):1059-63
pubmed: 21937192
Lancet Oncol. 2014 Nov;15(12):1303-10
pubmed: 25439688
Eur J Surg Oncol. 2016 May;42(5):650-6
pubmed: 27005806
Eur J Oncol Nurs. 2014 Apr;18(2):218-27
pubmed: 24246445
Breast Cancer Res Treat. 2004 Jul;86(2):95-106
pubmed: 15319562
Breast. 2010 Dec;19(6):506-15
pubmed: 20561790
Breast J. 2010 Jan-Feb;16(1):48-54
pubmed: 19889169
Breast Cancer Res Treat. 2002 Sep;75(1):51-64
pubmed: 12500934
Medicina (Kaunas). 2022 Jul 19;58(7):
pubmed: 35888673
Front Oncol. 2018 Jun 12;8:197
pubmed: 29946531
Br J Surg. 2019 May;106(6):720-728
pubmed: 30839104
Curr Breast Cancer Rep. 2013 Jun;5(2):134-144
pubmed: 26246870
Acta Oncol. 2000;39(3):399-405
pubmed: 10987238
Lymphat Res Biol. 2018 Apr;16(2):182-186
pubmed: 28956715
Breast. 2002 Feb;11(1):66-71
pubmed: 14965648
J Clin Oncol. 1986 Jun;4(6):929-41
pubmed: 3519883
Gland Surg. 2016 Apr;5(2):187-96
pubmed: 27047786
J Clin Oncol. 2008 Nov 10;26(32):5213-9
pubmed: 18838709
Ann Surg Oncol. 2021 Jun;28(6):3223-3229
pubmed: 33170457
Cancer. 2002 May 15;94(10):2542-51
pubmed: 12173319
Breast Cancer Res Treat. 2013 Aug;140(3):485-94
pubmed: 23912961
N Engl J Med. 2003 Aug 7;349(6):546-53
pubmed: 12904519
J Clin Oncol. 2013 Oct 20;31(30):3758-63
pubmed: 24043733
Breast Cancer Res Treat. 2010 Apr;120(3):649-54
pubmed: 20180016
Cancer. 2008 Jun 15;112(12):2809-19
pubmed: 18428212
Biomed Res Int. 2013;2013:807569
pubmed: 23853774
Support Care Cancer. 2015 Oct;23(10):3103-12
pubmed: 25752884
J Clin Oncol. 2016 Mar 1;34(7):691-8
pubmed: 26644530
J Breast Cancer. 2021 Feb;24(1):63-74
pubmed: 33634621
Surgery. 2014 Nov;156(5):1261-8
pubmed: 25444319
Cochrane Database Syst Rev. 2015 May 21;(5):CD003475
pubmed: 25994425
Ann Surg Oncol. 2007 Jun;14(6):1890-5
pubmed: 17479341
Lancet Oncol. 2013 Dec;14(13):1269-77
pubmed: 24225155
Clin Breast Cancer. 2021 Apr;21(2):128-142
pubmed: 33771439
Front Oncol. 2020 Sep 25;10:571091
pubmed: 33072603
Lancet. 2014 Feb 15;383(9917):603-13
pubmed: 24224997
Breast Cancer. 2018 May;25(3):309-314
pubmed: 29397555
Breast Cancer Res Treat. 2016 Aug;158(3):421-32
pubmed: 27444925
Cold Spring Harb Perspect Med. 2022 May 27;12(5):
pubmed: 35074795
Eur J Vasc Endovasc Surg. 1996 Nov;12(4):412-7
pubmed: 8980428
Lymphat Res Biol. 2022 Dec;20(6):618-628
pubmed: 35099283
Lymphology. 2013 Dec;46(4):184-92
pubmed: 25141461
J Clin Oncol. 2008 Nov 10;26(32):5220-6
pubmed: 18838708
Breast J. 2020 Mar;26(3):454-457
pubmed: 31562688
Ann Surg Oncol. 2015 Oct;22(10):3296-301
pubmed: 26202566
Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1263-70
pubmed: 26122375
Plast Reconstr Surg. 2013 Jun;131(6):1286-1298
pubmed: 23714790
PLoS One. 2016 Feb 26;11(2):e0150285
pubmed: 26919589
Lymphology. 2013 Jun;46(2):85-96
pubmed: 24354107
Ann Surg Oncol. 2019 Oct;26(11):3446-3454
pubmed: 31240591
Breast Cancer Res Treat. 2018 Nov;172(1):83-91
pubmed: 30062571
J Am Coll Surg. 2008 May;206(5):1038-42; discussion 1042-4
pubmed: 18471751
N Engl J Med. 2004 Sep 2;351(10):971-7
pubmed: 15342805
Lancet Oncol. 2016 Sep;17(9):e392-405
pubmed: 27599144
Breast Cancer Res Treat. 2003 May;79(1):47-57
pubmed: 12779081
Contemp Clin Trials. 2009 May;30(3):233-45
pubmed: 19171204
J Pain Symptom Manage. 1992 Feb;7(2):110-6
pubmed: 1573284
Ann Surg Oncol. 2014 Apr;21(4):1189-94
pubmed: 24522988
Plast Reconstr Surg. 2015 Jan;135(1):277-285
pubmed: 25285683
Cancer Biol Med. 2018 Nov;15(4):452-460
pubmed: 30766755
Rehabil Oncol. 2014;32(1):13-21
pubmed: 25346950
Breast Cancer Res Treat. 2016 Aug;159(1):1-14
pubmed: 27460637
Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2734-46
pubmed: 20978176
J Clin Oncol. 2006 Jun 20;24(18):2765-72
pubmed: 16702582
JAMA. 2013 Oct 9;310(14):1455-61
pubmed: 24101169
Curr Breast Cancer Rep. 2017 Jun;9(2):111-121
pubmed: 28894513
Lymphat Res Biol. 2011;9(2):93-9
pubmed: 21688978
Breast. 2016 Aug;28:29-36
pubmed: 27183497
Br J Surg. 2015 Aug;102(9):1071-8
pubmed: 26040263
Clin Breast Cancer. 2012 Apr;12(2):133-7
pubmed: 22444720
Breast Cancer (Dove Med Press). 2015 Oct 15;7:345-52
pubmed: 26527899
Lymphology. 2010 Sep;43(3):118-27
pubmed: 21226414
Ann Plast Surg. 2016 Sep;77(3):337-40
pubmed: 26418771
Breast Cancer Res Treat. 2015 Jun;151(2):393-403
pubmed: 25940996
Ann Oncol. 2007 Apr;18(4):639-46
pubmed: 17018707
Microsurgery. 2014 Sep;34(6):421-4
pubmed: 24677148
BMJ. 2020 Aug 19;370:m2836
pubmed: 32816842
Radiology. 1991 Jul;180(1):177-84
pubmed: 2052688