Analysis of Stable Chelate-free Gadolinium Loaded Titanium Dioxide Nanoparticles for MRI-Guided Radionuclide Stimulated Cancer Treatment.
MRI
Titanium dioxide
cancer
cerenkov radiation
colorimetric assay
magnetic resonance imaging
reactive oxygen species
relaxivity
Journal
Current analytical chemistry
ISSN: 1573-4110
Titre abrégé: Curr Anal Chem
Pays: United Arab Emirates
ID NLM: 101261866
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
entrez:
23
12
2022
pubmed:
24
12
2022
medline:
24
12
2022
Statut:
ppublish
Résumé
Recent studies demonstrate that titanium dioxide nanoparticles (TiO Given the use of gadolinium (Gd) chelates as effective contrast agents for magnetic resonance imaging (MRI), this study aims to (1) develop hybrid TiO A chelate-free, heat-induced method was used to load Gd onto TiO A simple colorimetric assay accurately determined both the loading and stability of the NPs compared with the expensive and complex ICP-MS method. Coating of the TiO This work demonstrates that Arsenazo III colorimetric assay can substitute ICP-MS for determining the loading and stability of Gd-doped TiO
Sections du résumé
Background
UNASSIGNED
Recent studies demonstrate that titanium dioxide nanoparticles (TiO
Objective
UNASSIGNED
Given the use of gadolinium (Gd) chelates as effective contrast agents for magnetic resonance imaging (MRI), this study aims to (1) develop hybrid TiO
Methods
UNASSIGNED
A chelate-free, heat-induced method was used to load Gd onto TiO
Results
UNASSIGNED
A simple colorimetric assay accurately determined both the loading and stability of the NPs compared with the expensive and complex ICP-MS method. Coating of the TiO
Conclusion
UNASSIGNED
This work demonstrates that Arsenazo III colorimetric assay can substitute ICP-MS for determining the loading and stability of Gd-doped TiO
Identifiants
pubmed: 36561765
doi: 10.2174/1573411018666220321102736
pmc: PMC9770661
mid: NIHMS1854710
doi:
Types de publication
Journal Article
Langues
eng
Pagination
826-835Subventions
Organisme : NCI NIH HHS
ID : P30 CA091842
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA260855
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB030987
Pays : United States
Déclaration de conflit d'intérêts
CONFLICT OF INTEREST The authors declare no conflict of interest, financial or otherwise.
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