Contrast-induced acute kidney injury and its contemporary prevention.

PCI acute kidney injury chronic renal insufficiency contrast-induced acute kidney injury nephrotoxicity prevention

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2022
Historique:
received: 18 10 2022
accepted: 22 11 2022
entrez: 23 12 2022
pubmed: 24 12 2022
medline: 24 12 2022
Statut: epublish

Résumé

The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney injury (CI-AKI). At present, effective therapy of CI-AKI is rather limited. Effective prevention of CI-AKI therefore becomes crucially important. This review presents an in-depth discussion of CI-AKI incidence, pathogenesis, risk prediction, current preventive strategies, and novel treatment possibilities. The review also discusses the difference between CI-AKI incidence following intraarterial and intravenous CM administration. Factors contributing to the development of CI-AKI are considered in conjunction with the mechanism of acute kidney damage. The need for ultimate risk estimation and the prediction of CI-AKI is stressed. Possibilities of CI-AKI prevention is evaluated within the spectrum of existing preventive measures aimed at reducing kidney injury. In particular, the review discusses intravenous hydration regimes and pre-treatment with statins and N-acetylcysteine. The review further focuses on emerging alternative imaging technologies, alternative intravascular diagnostic and interventional procedures, and new methods for intravenous hydration guidance; it discusses the applicability of those techniques in complex procedures and their feasibility in current practise. We put emphasis on contemporary interventional cardiology imaging methods, with a brief discussion of CI-AKI in non-vascular and non-cardiologic imaging and interventional studies.

Identifiants

pubmed: 36561776
doi: 10.3389/fcvm.2022.1073072
pmc: PMC9763312
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1073072

Informations de copyright

Copyright © 2022 Sůva, Kala, Poloczek, Kaňovský, Štípal, Radvan, Hlasensky, Hudec, Brázdil and Řehořová.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Marek Sůva (M)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Petr Kala (P)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Martin Poloczek (M)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Jan Kaňovský (J)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Roman Štípal (R)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Martin Radvan (M)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Jiří Hlasensky (J)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Martin Hudec (M)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Vojtěch Brázdil (V)

Department of Internal Medicine and Cardiology, University Hospital, Brno, Czechia.
Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, Brno, Czechia.

Jitka Řehořová (J)

Department of Internal Medicine and Gastroenterology, University Hospital, Brno, Czechia.

Classifications MeSH