Mapping of Fatty Aldehydes in the Diabetic Rat Brain Using On-Tissue Chemical Derivatization and Air-Flow-Assisted Desorption Electrospray Ionization-Mass Spectrometry Imaging.

Rats Animals Spectrometry, Mass, Electrospray Ionization / methods Aldehydes Brain / diagnostic imaging Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods Diabetes Mellitus
air-flow-assisted desorption electrospray ionization-mass spectrometry imaging brain tissue diabetic encephalopathy fatty aldehyde on-tissue chemical derivatization

Journal

Journal of proteome research
ISSN: 1535-3907
Titre abrégé: J Proteome Res
Pays: United States
ID NLM: 101128775

Informations de publication

Date de publication:
06 01 2023
Historique:
pubmed: 24 12 2022
medline: 10 1 2023
entrez: 23 12 2022
Statut: ppublish

Résumé

Fatty aldehydes (FALs) are involved in various biological processes, and their abnormal metabolism is related to the occurrence and development of neurological diseases. Because of their low ionization efficiency, methods for

Identifiants

DOI: 10.1021/acs.jproteome.2c00445 PMID: 36564034
pubmed: 36564034
doi: 10.1021/acs.jproteome.2c00445
doi:

Substances chimiques

fatty aldehyde 0
Aldehydes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

36-46

Auteurs

Xianyue Meng (X)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Yanhua Liu (Y)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Meiling Huo (M)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Shu Yang (S)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Key Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Minzu University of China, Beijing 100081, P. R. China.

Xin Zhang (X)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Lu Tian (L)

New Drug Safety Evaluation Center, Chinese Academy of Medical Sciences, Beijing 100050, China.

Wanfang Li (W)

New Drug Safety Evaluation Center, Chinese Academy of Medical Sciences, Beijing 100050, China.

Jinfeng Wei (J)

New Drug Safety Evaluation Center, Chinese Academy of Medical Sciences, Beijing 100050, China.

Zhaoying Wang (Z)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Zhi Zhou (Z)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Yanhua Chen (Y)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.

Zhonghua Wang (Z)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.
ORCID: 0000-0003-1553-8367

Zeper Abliz (Z)

Key Laboratory of Mass Spectrometry Imaging and Metabolomics, Minzu University of China, National Ethnic Affairs Commission, Beijing 100081, China.
Center for Imaging and Systems Biology, College of Life and Environmental Sciences, Minzu University of China, 27 Zhongguancun South Avenue, Beijing 100081, China.
Key Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Minzu University of China, Beijing 100081, P. R. China.
ORCID: 0000-0002-4876-2392

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Eucaryotes › Animaux › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse ESI › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Composés chimiques organiques › Aldéhydes › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse MALDI › Mapping of Fatty Aldehydes in the Diabetic Rat...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Mapping of Fatty Aldehydes in the Diabetic Rat...