Recent Emerging Trend in Stem Cell Therapy Risk Factors.

Humans Cell Differentiation Multipotent Stem Cells Stem Cell Transplantation Risk Factors
MSC Stem cells cell therapy multipotent pluripotent risk factors

Journal

Current stem cell research & therapy
ISSN: 2212-3946
Titre abrégé: Curr Stem Cell Res Ther
Pays: United Arab Emirates
ID NLM: 101272517

Informations de publication

Date de publication:
2023
Historique:
received: 17 07 2022
revised: 15 10 2022
accepted: 08 11 2022
medline: 14 7 2023
pubmed: 26 12 2022
entrez: 25 12 2022
Statut: ppublish

Résumé

Different types of stem cells have remarkable characteristics such as high proliferation rate, multi/pluripotency, self-renewal, and broad differentiation that can effectively treat diseases, cancers, and damage. Despite abundant therapeutic applications of stem cells in medical science, numerous risks threaten stem cell transplantation. Tumor development, immune response, cellular senescence, dosage effects, and administration timing are critical risks that should be considered in stem cell therapy. Hence, an investigation of possible risks is required before utilizing stem cell-based medicinal products in the clinical phase and human trials. This review aims to survey the literature and perspectives on the advantages and risks associated with pluripotent and multipotent stem cells.

Identifiants

DOI: 10.2174/1574888X18666221223104859 PMID: 36567298
pubmed: 36567298
pii: CSCR-EPUB-128410
doi: 10.2174/1574888X18666221223104859
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1076-1089

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Bahareh Pourjabbar (B)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Forough Shams (F)

Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Maryam Moghadam (M)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Milad Ahani-Nahayati (M)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Arezo Azari (A)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Farshid Sefat (F)

Department of Biomedical and Electronics Engineering, School of Engineering, University of Bradford, Bradford, UK.
Interdisciplinary Research Centre in Polymer Science & Technology (Polymer IRC), University of Bradford, Bradford, UK.

Saeed Heidari Keshel (SH)

Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Medical Nanotechnology and Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Recent Emerging Trend in Stem Cell Therapy...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Recent Emerging Trend in Stem Cell Therapy...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches multipotentes › Recent Emerging Trend in Stem Cell Therapy...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation cellulaire › Transplantation de cellules souches › Recent Emerging Trend in Stem Cell Therapy...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Recent Emerging Trend in Stem Cell Therapy...