Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor.


Journal

Acta neuropathologica communications
ISSN: 2051-5960
Titre abrégé: Acta Neuropathol Commun
Pays: England
ID NLM: 101610673

Informations de publication

Date de publication:
25 12 2022
Historique:
received: 26 08 2022
accepted: 12 12 2022
entrez: 25 12 2022
pubmed: 26 12 2022
medline: 28 12 2022
Statut: epublish

Résumé

Regeneration of the neuromuscular junction (NMJ) leverages on extensive exchange of factors released from motor axon terminals (MATs), muscle fibers and perisynaptic Schwann cells (PSCs), among which hydrogen peroxide (H

Identifiants

pubmed: 36567321
doi: 10.1186/s40478-022-01495-5
pii: 10.1186/s40478-022-01495-5
pmc: PMC9791753
doi:

Substances chimiques

Connective Tissue Growth Factor 139568-91-5
Hydrogen Peroxide BBX060AN9V

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

189

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S006990/1
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s).

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Auteurs

Samuele Negro (S)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy.
U.O.C. Clinica Neurologica, Azienda Ospedale, University of Padua, 35128, Padua, Italy.

Fabio Lauria (F)

Institute of Biophysics, CNR Unit at Trento, 38123, Povo, Italy.

Marco Stazi (M)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy.

Toma Tebaldi (T)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123, Povo, Italy.
Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, 06520, USA.

Giorgia D'Este (G)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy.

Marco Pirazzini (M)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy.
Myology Center (CIR-Myo), University of Padua, 35129, Padua, Italy.

Aram Megighian (A)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy.
Padua Neuroscience Center, University of Padua, 35131, Padua, Italy.

Francesca Lessi (F)

Laboratory of Genomics, Pisa Science Foundation, 56017, San Giuliano Terme, Italy.

Chiara M Mazzanti (CM)

Laboratory of Genomics, Pisa Science Foundation, 56017, San Giuliano Terme, Italy.

Gabriele Sales (G)

Department of Biology, University of Padua, 35131, Padua, Italy.

Chiara Romualdi (C)

Department of Biology, University of Padua, 35131, Padua, Italy.

Silvia Fillo (S)

Center of Medical and Veterinary Research of the Ministry of Defence, 00184, Rome, Italy.

Florigio Lista (F)

Center of Medical and Veterinary Research of the Ministry of Defence, 00184, Rome, Italy.

James N Sleigh (JN)

Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
UCL Queen Square Motor Neuron Disease Centre, University College London, London, WC1N 3BG, UK.
UK Dementia Research Institute, University College London, London, WC1E 6BT, UK.

Andrew P Tosolini (AP)

Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
UCL Queen Square Motor Neuron Disease Centre, University College London, London, WC1N 3BG, UK.

Giampietro Schiavo (G)

Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
UCL Queen Square Motor Neuron Disease Centre, University College London, London, WC1N 3BG, UK.
UK Dementia Research Institute, University College London, London, WC1E 6BT, UK.

Gabriella Viero (G)

Institute of Biophysics, CNR Unit at Trento, 38123, Povo, Italy.

Michela Rigoni (M)

Department of Biomedical Sciences, University of Padua, 35131, Padua, Italy. michela.rigoni@unipd.it.
Myology Center (CIR-Myo), University of Padua, 35129, Padua, Italy. michela.rigoni@unipd.it.

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Classifications MeSH