Association of Statins With Nonculprit Coronary Lesions and Adverse Events (from the LRP Study).
Humans
Coronary Artery Disease
/ complications
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/ therapeutic use
Plaque, Atherosclerotic
/ complications
Acute Coronary Syndrome
/ complications
Lipids
Ultrasonography, Interventional
/ methods
Coronary Vessels
/ diagnostic imaging
Coronary Angiography
/ adverse effects
intravascular ultrasound
near-infrared spectroscopy
statin
vulnerable plaque
Journal
The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277
Informations de publication
Date de publication:
01 03 2023
01 03 2023
Historique:
received:
25
08
2022
revised:
24
10
2022
accepted:
26
11
2022
pubmed:
27
12
2022
medline:
8
2
2023
entrez:
26
12
2022
Statut:
ppublish
Résumé
Intravascular ultrasound and near-infrared spectroscopy can identify vulnerable coronary atherosclerotic plaques. In this LRP (Lipid-Rich Plaque) substudy, we evaluated the association of statins with nonculprit lesion arterial wall lipidic content and subsequent nonculprit major adverse cardiac events. Patients from the LRP study with known statin use were included. We divided the patients into 2 cohorts-"statin therapy" and "statin-naïve"-upon presentation and then described the intravascular ultrasound and near-infrared spectroscopy analysis based on maximum 4-mm lipid core burden index (maxLCBI
Identifiants
pubmed: 36571935
pii: S0002-9149(22)01264-4
doi: 10.1016/j.amjcard.2022.11.048
pii:
doi:
Substances chimiques
Hydroxymethylglutaryl-CoA Reductase Inhibitors
0
Lipids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
82-89Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.