Endoluminal ultrasound versus magnetic resonance imaging in assessment of rectal cancer after neoadjuvant therapy.
Colorectal cancer
EUS
Neo-adjuvant therapy
Journal
BMC gastroenterology
ISSN: 1471-230X
Titre abrégé: BMC Gastroenterol
Pays: England
ID NLM: 100968547
Informations de publication
Date de publication:
27 Dec 2022
27 Dec 2022
Historique:
received:
02
09
2022
accepted:
20
12
2022
entrez:
27
12
2022
pubmed:
28
12
2022
medline:
30
12
2022
Statut:
epublish
Résumé
Accurate rectal tumor staging guides the choice of treatment options. EUS and MRI are the main modalities for staging. To compare the performance of EUS and MRI for loco-regional staging of anorectal cancer after neo-adjuvant therapy. Seventy-three (37 male, 36 female) patients with rectal cancer after neo-adjuvant chemoradiotherapy were enrolled. Histopathological staging after surgery were used as reference for comparing the yield of loco-regional staging for EUS and MRI. EUS and MRI were done 1 month after completion of neo-adjuvant therapy. Regarding post-surgical T staging, eight patients had early tumor (T2 = 16 and T1 = 9) and thirty six were locally advanced (T3 = 36), while N staging, forty patients with negative nodes and 33 were positive (N1 = 22 and N2 = 11). Comparing EUS to MRI, it showed a higher sensitivity (95.7% vs. 78.7%), specificity (84.6% vs. 68.0%) and accuracy (91.8% vs. 75.3%) for staging early and locally advanced tumor. Also, it had a higher sensitivity (78.8% vs. 69.7%), specificity (75.0% vs. 65.0%) and accuracy (76.7% vs. 67.1%) for detection of lymph nodes. EUS appears to be more accurate than MRI in loco-regional staging of rectal carcinoma after neo-adjuvant therapy.
Sections du résumé
BACKGROUND
BACKGROUND
Accurate rectal tumor staging guides the choice of treatment options. EUS and MRI are the main modalities for staging.
AIM OF THE WORK
OBJECTIVE
To compare the performance of EUS and MRI for loco-regional staging of anorectal cancer after neo-adjuvant therapy.
METHODS
METHODS
Seventy-three (37 male, 36 female) patients with rectal cancer after neo-adjuvant chemoradiotherapy were enrolled. Histopathological staging after surgery were used as reference for comparing the yield of loco-regional staging for EUS and MRI. EUS and MRI were done 1 month after completion of neo-adjuvant therapy.
RESULTS
RESULTS
Regarding post-surgical T staging, eight patients had early tumor (T2 = 16 and T1 = 9) and thirty six were locally advanced (T3 = 36), while N staging, forty patients with negative nodes and 33 were positive (N1 = 22 and N2 = 11). Comparing EUS to MRI, it showed a higher sensitivity (95.7% vs. 78.7%), specificity (84.6% vs. 68.0%) and accuracy (91.8% vs. 75.3%) for staging early and locally advanced tumor. Also, it had a higher sensitivity (78.8% vs. 69.7%), specificity (75.0% vs. 65.0%) and accuracy (76.7% vs. 67.1%) for detection of lymph nodes.
CONCLUSION
CONCLUSIONS
EUS appears to be more accurate than MRI in loco-regional staging of rectal carcinoma after neo-adjuvant therapy.
Identifiants
pubmed: 36575373
doi: 10.1186/s12876-022-02628-9
pii: 10.1186/s12876-022-02628-9
pmc: PMC9793528
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
542Informations de copyright
© 2022. The Author(s).
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