A Homochiral Poly(2-oxazoline)-based Membrane for Efficient Enantioselective Separation.
Chiral Resolution
Chirality
Homochiral Polymers
Membranes
Poly(2-Oxazoline)s
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
13 Feb 2023
13 Feb 2023
Historique:
received:
16
08
2022
pubmed:
29
12
2022
medline:
29
12
2022
entrez:
28
12
2022
Statut:
ppublish
Résumé
Chiral separation membranes have shown great potential for the efficient separation of racemic mixtures into enantiopure components for many applications, such as in the food and pharmaceutical industries; however, scalable fabrication of membranes with both high enantioselectivity and flux remains a challenge. Herein, enantiopure S-poly(2,4-dimethyl-2-oxazoline) (S-PdMeOx) macromonomers were synthesized and used to prepare a new type of enantioselective membrane consisting of a chiral S-PdMeOx network scaffolded by graphene oxide (GO) nanosheets. The S-PdMeOx-based membrane showed a near-quantitative enantiomeric excess (ee) (98.3±1.7 %) of S-(-)-limonene over R-(+)-limonene and a flux of 0.32 mmol m
Identifiants
pubmed: 36577702
doi: 10.1002/anie.202212139
pmc: PMC10107185
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202212139Subventions
Organisme : Australian Research Council
ID : DP210101758
Organisme : Australian Research Council
ID : FT190100572
Organisme : Australian Research Council
ID : FL200100049
Informations de copyright
© 2022 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.
Références
Nat Chem. 2021 Dec;13(12):1186-1191
pubmed: 34650235
Curr Top Med Chem. 2011;11(7):760-70
pubmed: 21291399
Chem Soc Rev. 2008 Jun;37(6):1243-63
pubmed: 18497936
Angew Chem Int Ed Engl. 2021 Jun 1;60(23):12781-12785
pubmed: 33792135
Nat Commun. 2019 Jun 7;10(1):2500
pubmed: 31175298
Angew Chem Int Ed Engl. 2023 Feb 13;62(8):e202212139
pubmed: 36577702
Chirality. 2011 May;23(5):379-82
pubmed: 21488105
J Chromatogr A. 2016 Oct 7;1467:33-55
pubmed: 27524302
Macromol Rapid Commun. 2012 Oct 15;33(19):1600-12
pubmed: 22760956
Angew Chem Int Ed Engl. 2018 Dec 21;57(52):17130-17134
pubmed: 30370963
Angew Chem Int Ed Engl. 2009;48(43):7978-94
pubmed: 19768817
Amino Acids. 2018 Nov;50(11):1549-1556
pubmed: 30073606
Angew Chem Int Ed Engl. 2015 Sep 14;54(38):11214-8
pubmed: 26352031