Impact of daily vitamin D
children
deficiency
polymorphism
rs2282679
supplement
vitamin D
Journal
Frontiers in nutrition
ISSN: 2296-861X
Titre abrégé: Front Nutr
Pays: Switzerland
ID NLM: 101642264
Informations de publication
Date de publication:
2022
2022
Historique:
received:
04
10
2022
accepted:
11
11
2022
entrez:
29
12
2022
pubmed:
30
12
2022
medline:
30
12
2022
Statut:
epublish
Résumé
The rs2282679 polymorphism in the vitamin D binding protein (DBP) gene may influence the response to vitamin D supplementation. Therefore, we examine the effect of 1-year vitamin D supplementation on vitamin D deficiency (VDD) with the interaction of rs2282679 polymorphism in overweight and obese children and adolescents. The participants ( The mean of 25(OH)D values at baseline for participants with the TT, TG, and GG genotypes were 15.4, 14.4, and 10.8 ng/mL, respectively, and were not different between the three genotype groups ( Response to vitamin D supplementation by three doses of 600, 1,000, and 2,000 IU could not be affected by rs2282679 polymorphism during 12 months in overweight and obese children and adolescents.
Sections du résumé
Background
UNASSIGNED
The rs2282679 polymorphism in the vitamin D binding protein (DBP) gene may influence the response to vitamin D supplementation. Therefore, we examine the effect of 1-year vitamin D supplementation on vitamin D deficiency (VDD) with the interaction of rs2282679 polymorphism in overweight and obese children and adolescents.
Materials and methods
UNASSIGNED
The participants (
Results
UNASSIGNED
The mean of 25(OH)D values at baseline for participants with the TT, TG, and GG genotypes were 15.4, 14.4, and 10.8 ng/mL, respectively, and were not different between the three genotype groups (
Conclusion
UNASSIGNED
Response to vitamin D supplementation by three doses of 600, 1,000, and 2,000 IU could not be affected by rs2282679 polymorphism during 12 months in overweight and obese children and adolescents.
Identifiants
pubmed: 36579074
doi: 10.3389/fnut.2022.1061496
pmc: PMC9792175
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1061496Informations de copyright
Copyright © 2022 Asghari, Yuzbashian, Nikparast, Najd Hassan Bonab, Mahdavi, Daneshpour, Hosseinpanah and Mirmiran.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
PLoS One. 2019 Dec 12;14(12):e0226215
pubmed: 31830090
Horm Cancer. 2013 Aug;4(4):242-50
pubmed: 23456391
Eur J Endocrinol. 2013 Oct 01;169(5):559-67
pubmed: 23935129
South Med J. 2005 Oct;98(10):1024-7
pubmed: 16295817
Nutr J. 2013 Apr 04;12:39
pubmed: 23556437
Am J Clin Nutr. 2000 Sep;72(3):690-3
pubmed: 10966885
Clin Nutr ESPEN. 2019 Feb;29:59-64
pubmed: 30661702
Sci Rep. 2017 Jan 12;7:40593
pubmed: 28079136
Nutrition. 2020 Jul - Aug;75-76:110761
pubmed: 32289634
J Pediatr (Rio J). 2021 May-Jun;97(3):273-279
pubmed: 33022267
Lancet. 2010 Jul 17;376(9736):180-8
pubmed: 20541252
Br J Nutr. 2017 Mar;117(6):829-838
pubmed: 28382877
Am J Clin Nutr. 2010 Dec;92(6):1393-8
pubmed: 20943799
J Bone Miner Res. 2011 Jul;26(7):1609-16
pubmed: 21416506
Nutrients. 2020 Aug 27;12(9):
pubmed: 32867112
Endocr J. 2012;59(11):1007-14
pubmed: 22785457
J Bone Miner Res. 2017 Mar;32(3):498-507
pubmed: 27683185
Clin Biochem. 2009 Jul;42(10-11):1174-7
pubmed: 19302999
Int J Vitam Nutr Res. 2020 Jun;90(3-4):339-345
pubmed: 32517587
Curr Opin Nephrol Hypertens. 2011 Jul;20(4):331-6
pubmed: 21654390
Nucleic Acids Res. 1988 Feb 11;16(3):1215
pubmed: 3344216
Am J Epidemiol. 2009 Feb 15;169(4):505-14
pubmed: 19126586
Nutrients. 2021 Sep 04;13(9):
pubmed: 34578986
J Clin Endocrinol Metab. 2017 Aug 1;102(8):2941-2949
pubmed: 28575224
J Clin Endocrinol Metab. 2014 Jul;99(7):E1332-40
pubmed: 24694335
N Engl J Med. 2007 Jul 19;357(3):266-81
pubmed: 17634462
Horm Metab Res. 2016 Jan;48(1):27-34
pubmed: 25702786
Horm Res Paediatr. 2012;78(4):226-31
pubmed: 23128469
J Nutr. 2016 Nov;146(11):2312-2324
pubmed: 27683872
Public Health Nutr. 2010 May;13(5):654-62
pubmed: 19807937
J Clin Endocrinol Metab. 2014 Oct;99(10):E2133-7
pubmed: 25070320
J Clin Endocrinol Metab. 1990 Aug;71(2):405-13
pubmed: 2380336
J Cell Physiol. 2019 Aug;234(8):13977-13983
pubmed: 30624776
Eur J Nutr. 2021 Aug;60(5):2831-2840
pubmed: 33427961
J Clin Endocrinol Metab. 2009 Sep;94(9):3273-81
pubmed: 19549746
Hum Mol Genet. 2010 Jul 1;19(13):2739-45
pubmed: 20418485
PLoS One. 2014 Feb 27;9(2):e89907
pubmed: 24587115
Int J Prev Med. 2015 Jan 15;6:3
pubmed: 25789138