Fusobacteria behaving badly: Masquerading strains of strictly anaerobic Escherichiacoli misidentified due to the deletion of the hemB gene.


Journal

Anaerobe
ISSN: 1095-8274
Titre abrégé: Anaerobe
Pays: England
ID NLM: 9505216

Informations de publication

Date de publication:
Feb 2023
Historique:
received: 01 10 2022
revised: 01 12 2022
accepted: 05 12 2022
pubmed: 30 12 2022
medline: 25 2 2023
entrez: 29 12 2022
Statut: ppublish

Résumé

Three strictly anaerobic strains of Escherichia coli were misidentified as Fusobacterium mortiferum, due to a deletion of the hemB gene which is involved in anaerobic respiration. An unusual antimicrobial susceptibility pattern sparked the further diagnostic strategies that eventually identified these strains as true anaerobic E. coli This phenomenon is more common than appreciated and can have an impact on clinical practice including persistent and relapsing infections.

Identifiants

pubmed: 36580991
pii: S1075-9964(22)00175-5
doi: 10.1016/j.anaerobe.2022.102682
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102682

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest All authors had no conflict of interest. There was no funding for this study.

Auteurs

Bradley T Endres (BT)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Eugenie Basseres (E)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Diane M Citron (DM)

R. M. Alden Research Laboratory, Santa Monica, CA, 90404, USA.

Kerin L Tyrrell (KL)

R. M. Alden Research Laboratory, Santa Monica, CA, 90404, USA.

Khurshida Begum (K)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Chris Lancaster (C)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Yumi A Warren (YA)

R. M. Alden Research Laboratory, Santa Monica, CA, 90404, USA.

M Jahangir Alam (MJ)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Kevin W Garey (KW)

Department of Pharmacy Practice and Translational Research, University of Houston College of Pharmacy, Houston, TX, USA.

Ellie J C Goldstein (EJC)

R. M. Alden Research Laboratory, Santa Monica, CA, 90404, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA. Electronic address: ejcgmd@aol.com.

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Classifications MeSH