Visualization of both proximal M2-MCA segments in patients (the Tilted-V Sign) with acute M1-MCA occlusion stroke is associated with better procedural and prognostic outcomes.

Tilted-V Sign acute ischemic stroke collateral cerebral circulation endovascular thrombectomy large vessel occlusion

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2022
Historique:
received: 11 09 2022
accepted: 16 11 2022
entrez: 30 12 2022
pubmed: 31 12 2022
medline: 31 12 2022
Statut: epublish

Résumé

We aimed to assess the clinical significance of M1-MCA occlusion with visualization of both MCA-M2 segments ["Tilted-V sign" (TVS)] on initial CT angiography (CTA) in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT). Data for patients with consecutive AIS undergoing EVT for large vessel occlusion (LVO) in two academic centers are recorded in ongoing databases. Patients who underwent EVT for M1-MCA occlusions ≤ 6 h from symptom onset were included in this retrospective analysis. A total of 346 patients met the inclusion criteria; 189 (55%) had positive TVS. Patients with positive TVS were younger (68 ± 14 vs. 71 ± 14 years, Tilted-V Sign, an easily identifiable radiological marker, is associated with fewer recanalization attempts, better functional outcomes, and reduced mortality.

Identifiants

pubmed: 36582610
doi: 10.3389/fneur.2022.1041585
pmc: PMC9792472
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1041585

Informations de copyright

Copyright © 2022 Azriel, Horev, Avraham, Alguayn, Zlotnik, Ifergane, Sufaro, Dizitzer, Melamed, Shelef, Cohen, Leker and Honig.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

AJNR Am J Neuroradiol. 2008 Feb;29(2):247-52
pubmed: 17974616
Stroke. 2010 Jan;41(1):e25-33
pubmed: 19926836
Lancet. 1991 Jun 22;337(8756):1521-6
pubmed: 1675378
Neuroradiology. 2003 Jan;45(1):11-8
pubmed: 12525948
AJNR Am J Neuroradiol. 2009 Mar;30(3):525-31
pubmed: 19147716
AJNR Am J Neuroradiol. 2016 Jul;37(7):1296-302
pubmed: 26869467
Brain Behav. 2016 Jun 17;6(9):e00513
pubmed: 27688942
Lancet. 2000 May 13;355(9216):1670-4
pubmed: 10905241
Stroke. 2003 Sep;34(9):2279-84
pubmed: 12881609
Stroke. 1989 Jun;20(6):735-40
pubmed: 2728038
Sci Rep. 2016 Jun 14;6:27880
pubmed: 27296511
J Neuroimaging. 2014 Jul-Aug;24(4):354-8
pubmed: 24251821
Stroke. 2014 Jul;45(7):2010-7
pubmed: 24916912
Int J Stroke. 2008 Nov;3(4):230-6
pubmed: 18811738
Cerebrovasc Dis. 2017;44(3-4):113-121
pubmed: 28605743
Stroke. 2013 May;44(5):1480-8
pubmed: 23493735

Auteurs

Amit Azriel (A)

Department of Neurosurgery, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Anat Horev (A)

Department of Neurology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Elad Avraham (E)

Department of Neurosurgery, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Farouq Alguayn (F)

Department of Neurosurgery, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Yair Zlotnik (Y)

Department of Neurology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Gal Ifergane (G)

Department of Neurology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Yuval Zeev Sufaro (YZ)

Department of Neurosurgery, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Yotam Dizitzer (Y)

Department of Research Center, Soroka University Medical Center, Beer Sheva, Israel.

Israel Melamed (I)

Department of Neurosurgery, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Ilan Shelef (I)

Department of Radiology, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

José E Cohen (JE)

Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Ronen R Leker (RR)

Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Asaf Honig (A)

Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Classifications MeSH