Bulbar onset amyotrophic lateral sclerosis: A case report.
Amyotrophic lateral sclerosis
Dysphagia
Fasciculation
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
24
07
2022
revised:
12
10
2022
accepted:
07
11
2022
entrez:
30
12
2022
pubmed:
31
12
2022
medline:
31
12
2022
Statut:
epublish
Résumé
Amyotrophic lateral sclerosis is a rare progressive neurodegenerative disease that affects the brain and spinal cord nerve cells. The study highlights the role of early diagnosis and prognosis of bulbar onset ALS. We present a case of 60 years old female who presented with slurring of speech with a deviation of tongue and progressive dysphagia. With the role of Magnetic Resonance Imaging (MRI), Electromyography (EMG) and Nerve Conduction Study (NCS), a diagnosis of ALS was made. ALS is a progressive neurodegenerative disorder, and the presence of genioglossus muscle involvement at diagnosis implies a shorter survival. It mandates multidisciplinary aspects requiring a professional opinion from neurologists, speech therapists, otolaryngologists, and electrophysiologists for effective treatment. Edaravone has antioxidant properties which counteract oxidative stress leading to neuronal injury in patients with ALS. ALS with bulbar onset can have a grave prognosis and hence requires a multidisciplinary approach toward effective treatment.
Identifiants
pubmed: 36582871
doi: 10.1016/j.amsu.2022.104889
pii: S2049-0801(22)01649-1
pmc: PMC9793157
doi:
Types de publication
Case Reports
Langues
eng
Pagination
104889Informations de copyright
© 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
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