Primary hepatic origin of a neuroendocrine tumor: A rare case report.
Case report
Hepatic resection
Liver primary neuroendocrine tumor
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
22
09
2022
revised:
26
10
2022
accepted:
13
11
2022
entrez:
30
12
2022
pubmed:
31
12
2022
medline:
31
12
2022
Statut:
epublish
Résumé
Neuroendocrine tumors are mainly located in gastrointestinal tract, pancreas and lungs. The primary hepatic origin of neuroendocrine tumors is extremely rare. A 57-year-old female with a history of cholecystectomy presented to our hospital for right upper abdominal pain lasting for 2 months. Abdominal computed tomography revealed a large exophytic soft-tissue mass in the left liver lobe. Tumor markers were within the normal range. Octreoscan confirmed the primary hepatic origin of neuroendocrine tumor. The patient underwent left hepatic resection. Pathological and immunohistochemical examination of the resected specimen showed a well-differentiated grade 2 neuroendocrine tumor. Primary hepatic neuroendocrine tumors represent rare hepatic tumors. These tumors may occur at any age with an average of 50 years. Diagnosis algorithm includes two key steps: firstly, the confirmation of the endocrine nature of the tumor and secondly the confirmation of its primary nature. Neuroendocrine tumors are a very rare entity. The primary hepatic location is exceptional. The diagnosis is based on pathological and immunohistochemical examination as well as the result of the octreoscan.
Identifiants
pubmed: 36582882
doi: 10.1016/j.amsu.2022.104937
pii: S2049-0801(22)01697-1
pmc: PMC9793152
doi:
Types de publication
Case Reports
Langues
eng
Pagination
104937Informations de copyright
© 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
Déclaration de conflit d'intérêts
The authors declared no potential conflicts of interest concerning research, authorship, and/or publication of the article.
Références
World J Surg Oncol. 2008 Aug 27;6:91
pubmed: 18727836
Ann Surg Oncol. 2003 Dec;10(10):1171-5
pubmed: 14654473
Hepatobiliary Pancreat Dis Int. 2010 Feb;9(1):44-8
pubmed: 20133228
J Gastrointestin Liver Dis. 2015 Jun;24(2):241-4
pubmed: 26114185
Cases J. 2008 Nov 17;1(1):314
pubmed: 19014620
Cases J. 2009 Jan 27;2(1):90
pubmed: 19173727
Ann Hepatol. 2017 Aug 1;16(4):621-629
pubmed: 28611270
Int J Surg. 2020 Dec;84:226-230
pubmed: 33181358
World J Gastroenterol. 2009 May 21;15(19):2418-22
pubmed: 19452590
Surg Today. 2011 Dec;41(12):1655-60
pubmed: 21969201